1 to 10 of 12 literature results

• Discussion by Reinhard Länge et al. on "Degradation of the endocrine disrupting chemicals (EDCs) carbamazepine, clofibric acid, and iopromide by corona discharge over water" by Krause et al. [Chemosphere 75(2) (2009) 163-168].

  Authors: Reinhard Länge, Thomas Steger-Hartmann, Steffen A Borden, Hubertus Pietsch

  Source: Chemosphere. 2010 Jan

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• Derivation of an aquatic predicted no-effect concentration for the synthetic hormone, 17 alpha-ethinyl estradiol.

  17alpha-Ethinyl estradiol (EE2) is a synthetic estrogen widely used in combination with other steroid hormones in oral contraceptives and in the contr…

  Authors: Daniel J Caldwell, Frank Mastrocco, Thomas H Hutchinson, Reinhard Länge, Dagobert Heijerick, Colin Janssen, Paul D Anderson, John P Sumpter

  Source: Environmental science & technology. 2008 Oct 1

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• Incorporation of in silico biodegradability screening in early drug development--a feasible approach?

  The concentration of a pharmaceutical found in the environment is determined by the amount used by the patient, the excretion and metabolism pattern, …

  Authors: Thomas Steger-Hartmann, Reinhard Länge, Klaus Heuck

  Source: Environmental science and pollution research international. 2011 May

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• Environmental risk assessment of pharmaceutical drug substances--conceptual considerations.

  Drugs, i.e. active ingredients of human medicinal products, may be introduced into the environment after use in patients by sewage effluent pathways a…

  Authors: Reinhard Länge, Daniel Dietrich

  Source: Toxicology letters. 2002 May 10

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• Effects of synthetic gestagens on fish reproduction.

  Although it is well known that estrogenic steroidal hormones are able to affect the sexual development and reproduction of fish at low concentrations,…

  Authors: Jana Zeilinger, Thomas Steger-Hartmann, Edmund Maser, Stephan Goller, Richardus Vonk, Reinhard Länge

  Source: Environmental toxicology and chemistry / SETAC. 2009 Dec

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• Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow (Pimephales promelas).

  Indications of effects on fish endocrine system have been noted when exposed to effluents of sewage treatment plants and subsequently in the receiving…

  Authors: Melanie Zerulla, R Länge, T Steger-Hartmann, G Panter, T Hutchinson, D R Dietrich

  Source: Toxicology letters. 2002 May 10

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• Investigations into the environmental fate and effects of iopromide (ultravist), a widely used iodinated X-ray contrast medium.

  lodinated X-ray contrast media are pharmaceuticals which are biologically inert and metabolically stable during their passage through the body and are…

  Authors: Thomas Steger-Hartmann, Reinhard Länge, Hermann Schweinfurth, Matthias Tschampel, Irmgard Rehmann

  Source: Water research. 2002 Jan

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• Ecological risk assessment of endocrine disruptors.

  The European Centre for Ecotoxicology and Toxicology of Chemicals proposes a tiered approach for the ecological risk assessment of endocrine disruptor…

  Authors: T H Hutchinson, R Brown, K E Brugger, P M Campbell, M Holt, R Länge, P McCahon, L J Tattersfield, R van Egmond

  Source: Environmental health perspectives. 2000 Nov

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• Environmental risk assessment for the widely used iodinated X-ray contrast agent iopromide (Ultravist).

  Iodinated X-ray contrast media are diagnostic pharmaceuticals that are applied to enhance the contrast between organs or vessels examined and surround…

  Authors: T Steger-Hartmann, R Länge, H Schweinfurth

  Source: Ecotoxicology and environmental safety. 1999 Mar

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• Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances.

  The European Chemical Industry's aquatic research program for endocrine disrupters includes the development of an in vivo juvenile fathead minnow (Pim…

  Authors: Grace H Panter, Thomas H Hutchinson, Reinhard Länge, Christina M Lye, John P Sumpter, Melanie Zerulla, Charles R Tyler

  Source: Environmental toxicology and chemistry / SETAC. 2002 Feb

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