1 to 7 of 7 literature results

• Endogenous human microRNAs that suppress breast cancer metastasis.

  A search for general regulators of cancer metastasis has yielded a set of microRNAs for which expression is specifically lost as human breast cancer c…

  Authors: Sohail F Tavazoie, Claudio Alarcón, Thordur Oskarsson, David Padua, Qiongqing Wang, Paula D Bos, William L Gerald, Joan Massagué

  Source: Nature. 2008 Jan 10

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• TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4.

  Cells released from primary tumors seed metastases to specific organs by a nonrandom process, implying the involvement of biologically selective mecha…

  Authors: David Padua, Xiang H-F Zhang, Qiongqing Wang, Cristina Nadal, William L Gerald, Roger R Gomis, Joan Massagué

  Source: Cell. 2008 Apr 4

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• Latent bone metastasis in breast cancer tied to Src-dependent survival signals.

  Metastasis may arise years after removal of a primary tumor. The mechanisms allowing latent disseminated cancer cells to survive are unknown. We repor…

  Authors: Xiang H-F Zhang, Qiongqing Wang, William Gerald, Clifford A Hudis, Larry Norton, Marcel Smid, John A Foekens, Joan Massagué

  Source: Cancer cell. 2009 Jul 7

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• ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis.

  Bone metastasis is mediated by complex interactions between tumor cells and resident stromal cells in the bone microenvironment. The functions of meta…

  Authors: Xin Lu, Qiongqing Wang, Guohong Hu, Catherine Van Poznak, Martin Fleisher, Michael Reiss, Joan Massagué, Yibin Kang

  Source: Genes & development. 2009 Aug 15

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• A FoxO-Smad synexpression group in human keratinocytes.

  Transforming growth factor beta (TGF-beta) signals through activation of Smad transcription factors. Activated Smad proteins associate with different …

  Authors: Roger R Gomis, Claudio Alarcón, Wei He, Qiongqing Wang, Joan Seoane, Alex Lash, Joan Massagué

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2006 Aug 22

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• Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family.

  Pma1-D378N is a misfolded plasma membrane protein in yeast that is prevented from delivery to the cell surface and targeted instead for ER-associated …

  Authors: Qiongqing Wang, Amy Chang

  Source: The EMBO journal. 2003 Aug 1

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• Sphingoid base synthesis is required for oligomerization and cell surface stability of the yeast plasma membrane ATPase, Pma1.

  The plasma membrane H(+)-ATPase, Pma1, is an essential and long-lived integral membrane protein. Previous work has demonstrated that the Pma1-D378N mu…

  Authors: Qiongqing Wang, Amy Chang

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2002 Oct 1

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