1 to 10 of 12 literature results

• Intramolecular cyclopropene-furan [2 + 4] cycloaddition followed by a cyclopropylcarbinyl rearrangement to synthesize the BCD rings of cortistatin A.

  Synthesis of the BCD ring system of cortistatin A has been accomplished in 9 steps and 30% overall yield starting from commercially available 2-methyl…

  Authors: Philip Magnus, Ryan Littich

  Source: Organic letters. 2009 Sep 3

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• Concise syntheses of (-)-galanthamine and (+/-)-codeine via intramolecular alkylation of a phenol derivative.

  Suzuki coupling of 7 to 8 gave the biphenyl derivative 9. Reaction of 9 with ethyl vinyl ether/bromine/base gave 10, which on treatment with CsF/DMF a…

  Authors: Philip Magnus, Neeraj Sane, Benjamin P Fauber, Vince Lynch

  Source: Journal of the American Chemical Society. 2009 Nov 11

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• Synthesis of the tetrahydroisoquinoline alkaloid (+/-)-renieramycin G and A (+/-)-lemonomycinone analogue from a common intermediate.

  The total synthesis of tetrahydroisoquinoline alkaloids (+/-)-renieramycin G (4) and a lemonomycinone analogue (7) is described. A general strategy to…

  Authors: Philip Magnus, Kenneth S Matthews

  Source: Journal of the American Chemical Society. 2005 Sep 14

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• Synthesis of carbamates from diethoxycarbonyl hydrazine derivatives by E1cB eliminative cleavage of the N-N'-bond rather than reduction.

  Treatment of diethoxycarbonyl hydrazine derivatives with methyl bromoacetate/Cs(2)CO(3)/MeCN at 50 degrees C followed by heating to 80 degrees C resul…

  Authors: Philip Magnus, Negar Garizi, Kimberly A Seibert, Alexandra Ornholt

  Source: Organic letters. 2009 Dec 17

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• An expedient formal total synthesis of (-)-diazonamide A via a powerful, stereoselective O-aryl to C-aryl migration to form the C10 quaternary center.

  During the course of studies on the synthesis of diazonamide A 1, an unusual O-aryl into C-aryl rearrangement was discovered that allows partial contr…

  Authors: Chi-Ming Cheung, Frederick W Goldberg, Philip Magnus, Claire J Russell, Rachel Turnbull, Vince Lynch

  Source: Journal of the American Chemical Society. 2007 Oct 10

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• Thermal and acid-catalyzed Hofmann-Martius rearrangement of 3-N-aryl-2-oxindoles into 3-(arylamino)-2-oxindoles.

  reaction: see text] The Hofmann-Martius rearrangement of 3-N-aryl-2-oxindoles into 3-(arylamino)-2-oxindoles under thermal and acid-catalyzed conditio…

  Authors: Philip Magnus, Rachel Turnbull

  Source: Organic letters. 2006 Aug 3

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• Proposed biogenetic origin of secu'amamine A from allosecurinine: a model study to support the intermediacy of the putative aziridinium ion.

  reaction: see text] A model study to support the intermediacy of the aziridinium ion in the proposed biogenetic origin of secu'amamine A from allosecu…

  Authors: Philip Magnus, Angela I Padilla

  Source: Organic letters. 2006 Aug 3

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• Stereospecific synthesis of (+/-)-1,2-anhydro methyl rocaglate.

  The rocaglates and analogues thereof have recently become targets for synthesis because of their potent antitumor activity. One of the major difficult…

  Authors: Philip Magnus, Matthew A H Stent

  Source: Organic letters. 2005 Sep 1

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• A mild thermal and acid-catalyzed rearrangement of O-aryl ethers into ortho-hydroxy arenes.

  reaction: see text] An unusual rearrangement of an O-aryl ether to an ortho-hydroxyaryl system was discovered during our studies on the synthesis of d…

  Authors: Frederick W Goldberg, Philip Magnus, Rachel Turnbull

  Source: Organic letters. 2005 Sep 29

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• New strategy for the synthesis of tetrahydroisoquinoline alkaloids.

  reaction: see text] A general strategy for the formation of 1,3-cis-substituted tetrahydroisoquinolines is described from ortho-iodo imines involving …

  Authors: Philip Magnus, Kenneth S Matthews, Vince Lynch

  Source: Organic letters. 2003 Jun 12

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