1 to 10 of 23 literature results

• Regulatory networks define phenotypic classes of human stem cell lines.

  Stem cells are defined as self-renewing cell populations that can differentiate into multiple distinct cell types. However, hundreds of different huma…

  Authors: Franz-Josef Müller, Louise C Laurent, Dennis Kostka, Igor Ulitsky, Roy Williams, Christina Lu, In-Hyun Park, Mahendra S Rao, Ron Shamir, Philip H Schwartz,…

  Source: Nature. 2008 Sep 18

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• Human cytomegalovirus infection causes premature and abnormal differentiation of human neural progenitor cells.

  Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects, largely manifested as central nervous system (CNS) disorders. T…

  Authors: Min Hua Luo, Holger Hannemann, Amit S Kulkarni, Philip H Schwartz, John M O'Dowd, Elizabeth A Fortunato

  Source: Journal of virology. 2010 Apr

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• Neonatal neural progenitor cells and their neuronal and glial cell derivatives are fully permissive for human cytomegalovirus infection.

  Congenital human cytomegalovirus (HCMV) infection causes central nervous system structural abnormalities and functional disorders, affecting both astr…

  Authors: Min Hua Luo, Philip H Schwartz, Elizabeth A Fortunato

  Source: Journal of virology. 2008 Oct

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• Redistribution of transcription start sites within the FMR1 promoter region with expansion of the downstream CGG-repeat element.

  Fragile X syndrome, the most common form of mental impairment, is caused by expansion of a (CGG)n trinucleotide repeat element located in the 5' untra…

  Authors: Alexandra Beilina, Flora Tassone, Philip H Schwartz, Parminder Sahota, Paul J Hagerman

  Source: Human molecular genetics. 2004 Mar 1

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• Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells.

  Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder that affects some adult carriers of pre-mutation alleles (55-200 C…

  Authors: Dolores Garcia Arocena, Christine K Iwahashi, Nelly Won, Alexandra Beilina, Anna L Ludwig, Flora Tassone, Philip H Schwartz, Paul J Hagerman

  Source: Human molecular genetics. 2005 Dec 1

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• Mammalian stem cells.

  Stem cells are quickly coming into focus of much biomedical research eventually aiming at the therapeutic applications for various disorders and traum…

  Authors: Alexey V Terskikh, Peter J Bryant, Philip H Schwartz

  Source: Pediatric research. 2006 Apr

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• Regulation of human neural precursor cells by laminin and integrins.

  Deciphering the factors that regulate human neural stem cells will greatly aid in their use as models of development and as therapeutic agents. The ex…

  Authors: Lisa A Flanagan, Liza M Rebaza, Stanislava Derzic, Philip H Schwartz, Edwin S Monuki

  Source: Journal of neuroscience research. 2006 Apr

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• Treatment reduces or stabilizes brain imaging abnormalities in patients with MPS I and II.

  BACKGROUND: The mucopolysaccharidoses (MPSs) are a family of lysosomal storage disorders caused by impaired glycosaminoglycan degradation. Characteris…

  Authors: Raymond Y Wang, Elizabeth Jane Cambray-Forker, Kirk Ohanian, David S Karlin, Kelly K Covault, Philip H Schwartz, Jose E Abdenur

  Source: Molecular genetics and metabolism. 2009 Dec

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• Human neural stem cell growth and differentiation in a gradient-generating microfluidic device.

  This paper describes a gradient-generating microfluidic platform for optimizing proliferation and differentiation of neural stem cells (NSCs) in cultu…

  Authors: Bong Geun Chung, Lisa A Flanagan, Seog Woo Rhee, Philip H Schwartz, Abraham P Lee, Edwin S Monuki, Noo Li Jeon

  Source: Lab on a chip. 2005 Apr

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• Asymmetric localization of LGN but not AGS3, two homologs of Drosophila pins, in dividing human neural progenitor cells.

  Human neural progenitor cells (hNPCs) can be recovered from postmortem human brains and used to study the molecular basis of neurogenesis. Human NPCs …

  Authors: Tannin J Fuja, Philip H Schwartz, Dan Darcy, Peter J Bryant

  Source: Journal of neuroscience research. 2004 Mar 15

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