1 to 10 of 222 literature results

• ETS rearrangements and prostate cancer initiation.

  The first recurrent translocation event in prostate cancer has been recently described; it results in the translocation of an ETS (E26 transformation …

  Authors: Brett S Carver, Jennifer Tran, Zhenbang Chen, Arkaitz Carracedo-Perez, Andrea Alimonti, Caterina Nardella, Anuradha Gopalan, Peter T Scardino, Carlos Cordon-Cardo, William Gerald,…

  Source: Nature. 2009 Feb 12

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• Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.

  Chromosomal translocations involving the ERG locus are frequent events in human prostate cancer pathogenesis; however, the biological role of aberrant…

  Authors: Brett S Carver, Jennifer Tran, Anuradha Gopalan, Zhenbang Chen, Safa Shaikh, Arkaitz Carracedo, Andrea Alimonti, Caterina Nardella, Shohreh Varmeh, Peter T Scardino,…

  Source: Nature genetics. 2009 May

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• The role of SPINK1 in ETS rearrangement-negative prostate cancers.

  ETS gene fusions have been characterized in a majority of prostate cancers; however, the key molecular alterations in ETS-negative cancers are unclear…

  Authors: Scott A Tomlins, Daniel R Rhodes, Jianjun Yu, Sooryanarayana Varambally, Rohit Mehra, Sven Perner, Francesca Demichelis, Beth E Helgeson, Bharathi Laxman, David S Morris,…

  Source: Cancer cell. 2008 Jun

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• Nomograms for staging, prognosis, and predicting treatment outcomes.

  Prostate cancer is a heterogeneous disease with a wide prognostic spectrum and a variety of treatment options. Such a complex clinical scenario has le…

  Authors: Karim Touijer, Peter T Scardino

  Source: Cancer. 2009 Jul 1

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• The 2008 European School of Oncology inside track conference, "predictive modeling in prostate cancer".

  The European School of Oncology (ESO) Inside Track Conference, "Predictive Modeling in Prostate Cancer," the first event ever dedicated to prediction …

  Authors: Riccardo Valdagni, Peter T Scardino, Louis Denis

  Source: Cancer. 2009 Jul 1

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• The surgical learning curve for prostate cancer control after radical prostatectomy.

  BACKGROUND: The learning curve for surgery--i.e., improvement in surgical outcomes with increasing surgeon experience--remains primarily a theoretical…

  Authors: Andrew J Vickers, Fernando J Bianco, Angel M Serio, James A Eastham, Deborah Schrag, Eric A Klein, Alwyn M Reuther, Michael W Kattan, J Edson Pontes, Peter T Scardino

  Source: Journal of the National Cancer Institute. 2007 Aug 1

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• Preoperative nomogram predicting the 10-year probability of prostate cancer recurrence after radical prostatectomy.

  An existing preoperative nomogram predicts the probability of prostate cancer recurrence, defined by prostate-specific antigen (PSA), at 5 years after…

  Authors: Andrew J Stephenson, Peter T Scardino, James A Eastham, Fernando J Bianco, Zohar A Dotan, Paul A Fearn, Michael W Kattan

  Source: Journal of the National Cancer Institute. 2006 May 17

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• TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy.

  A significant number of prostate cancers have been shown to have recurrent chromosomal rearrangements resulting in the fusion of the androgen-regulate…

  Authors: Anuradha Gopalan, Margaret A Leversha, Jaya M Satagopan, Qin Zhou, Hikmat A Al-Ahmadie, Samson W Fine, James A Eastham, Peter T Scardino, Howard I Scher, Satish K Tickoo,…

  Source: Cancer research. 2009 Feb 15

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• Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer.

  To identify biomarkers that discriminate the aggressive forms of prostate cancer, we performed gene expression profiling of prostate tumors using a ge…

  Authors: Xuesong Ouyang, Walter J Jessen, Hikmat Al-Ahmadie, Angel M Serio, Yong Lin, Weichung-Joseph Shih, Victor E Reuter, Peter T Scardino, Michael M Shen, Bruce J Aronow,…

  Source: Cancer research. 2008 Apr 1

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• Peter Lester Scardino--a genitourinary surgeon in third generation of the specialty: part 1.

  Authors: David A Bloom, Peter T Scardino

  Source: Urology. 2009 May

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