1 to 10 of 20 literature results

• Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors.

  The brain is a specialized immune site representing a unique tumor microenvironment. The availability of fresh brain tumor material for ex vivo analys…

  Authors: Joannes F M Jacobs, Albert J Idema, Kalijn F Bol, Stefan Nierkens, Oliver M Grauer, Pieter Wesseling, J André Grotenhuis, Peter M Hoogerbrugge, I Jolanda M de Vries, Gosse J Adema

  Source: Neuro-oncology. 2009 Aug

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• Therapeutic drug monitoring of voriconazole in a child with invasive aspergillosis requiring extracorporeal membrane oxygenation.

  We describe a patient with invasive pulmonary aspergillosis on extracorporeal membrane oxygenation therapy in which therapeutic drug monitoring and in…

  Authors: Roger J M Brüggemann, Tim Antonius, Arno van Heijst, Peter M Hoogerbrugge, David M Burger, Adilia Warris

  Source: Therapeutic drug monitoring. 2008 Dec

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• Regulation of MYCN expression in human neuroblastoma cells.

  BACKGROUND: Amplification of the MYCN gene in neuroblastoma (NB) is associated with a poor prognosis. However, MYCN-amplification does not automatical…

  Authors: Joannes F M Jacobs, Hans van Bokhoven, Frank N van Leeuwen, Christina A Hulsbergen-van de Kaa, I Jolanda M de Vries, Gosse J Adema, Peter M Hoogerbrugge, Arjan P M de Brouwer

  Source: BMC cancer. 2009

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• High-resolution genomic profiling of pediatric lymphoblastic lymphomas reveals subtle differences with pediatric acute lymphoblastic leukemias in the B-lineage.

  Lymphoblastic lymphoma (LBL) is one of the most frequent occurring pediatric non-Hodgkin lymphomas. In the WHO classification scheme, pediatric LBL is…

  Authors: Margit Schraders, Simon V van Reijmersdal, Eveline J Kamping, Johan H J M van Krieken, Ad Geurts van Kessel, Patricia J T A Groenen, Peter M Hoogerbrugge, Roland P Kuiper

  Source: Cancer genetics and cytogenetics. 2009 May

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• Selective cancer-germline gene expression in pediatric brain tumors.

  Cancer-germline genes (CGGs) code for immunogenic antigens that are present in various human tumors and can be targeted by immunotherapy. Their expres…

  Authors: Joannes F M Jacobs, Oliver M Grauer, Francis Brasseur, Peter M Hoogerbrugge, Pieter Wesseling, Corrie E Gidding, Mandy W M M van de Rakt, Carl G Figdor, Pierre G Coulie, I Jolanda M de Vries,…

  Source: Journal of neuro-oncology. 2008 Jul

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• Detection of the Candida antigen mannan in cerebrospinal fluid specimens from patients suspected of having Candida meningitis.

  Cerebrospinal fluid samples from five patients from which Candida cells were cultured were tested for the presence of mannan. Samples from four patien…

  Authors: Frans M Verduyn Lunel, Andreas Voss, Ed J Kuijper, L B S Gelinck, Peter M Hoogerbrugge, K L Liem, Bart Jan Kullberg, Paul E Verweij

  Source: Journal of clinical microbiology. 2004 Feb

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• Online focus groups as a tool to collect data in hard-to-include populations: examples from paediatric oncology.

  BACKGROUND: The purpose of this article is to describe and evaluate the methodology of online focus group discussions within the setting of paediatric…

  Authors: Kiek Tates, Marieke Zwaanswijk, Roel Otten, Sandra van Dulmen, Peter M Hoogerbrugge, Willem A Kamps, Jozien M Bensing

  Source: BMC medical research methodology. 2009

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• The Bt-DUX: development of a subjective measure of health-related quality of life in patients who underwent surgery for lower extremity malignant bone tumor.

  BACKGROUND: To examine the practical applicability, internal consistency, and validity of the Bt-DUX, a disease-specific Health Related Quality of Lif…

  Authors: W Peter Bekkering, Theodora P M Vliet Vlieland, Hendrik M Koopman, Gerard R Schaap, H W Bart Schreuder, Auke Beishuizen, Wim J E Tissing, Peter M Hoogerbrugge, Jacob K Anninga, Antonie H M Taminiau

  Source: Pediatric blood & cancer. 2009 Sep

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• Abnormal NT-pro-BNP levels in asymptomatic long-term survivors of childhood cancer treated with anthracyclines.

  BACKGROUND: Anthracycline-induced cardiotoxicity can cause serious health problems for an increasing number of survivors of childhood malignancies. Th…

  Authors: Annelies M C Mavinkurve-Groothuis, Jacqueline Groot-Loonen, Louise Bellersen, Milanthy S Pourier, Ton Feuth, Jos P M Bökkerink, Peter M Hoogerbrugge, Livia Kapusta

  Source: Pediatric blood & cancer. 2009 May

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• Interobserver, intraobserver and intrapatient reliability scores of myocardial strain imaging with 2-d echocardiography in patients treated with anthracyclines.

  Myocardial strain imaging with 2-D echocardiography is a relatively new noninvasive method to assess myocardial deformation. To determine the interobs…

  Authors: Annelies M C Mavinkurve-Groothuis, Gert Weijers, Jacqueline Groot-Loonen, Milanthy Pourier, Ton Feuth, Chris L de Korte, Peter M Hoogerbrugge, Livia Kapusta

  Source: Ultrasound in medicine & biology. 2009 Apr

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