1 to 5 of 5 literature results

• Reprogramming of human somatic cells to pluripotency with defined factors.

  Pluripotency pertains to the cells of early embryos that can generate all of the tissues in the organism. Embryonic stem cells are embryo-derived cell…

  Authors: In-Hyun Park, Rui Zhao, Jason A West, Akiko Yabuuchi, Hongguang Huo, Tan A Ince, Paul H Lerou, M William Lensch, George Q Daley

  Source: Nature. 2008 Jan 10

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• Human embryonic stem cell derivation from poor-quality embryos.

  During in vitro fertilization, embryos deemed clinically useless based on poor morphology are typically discarded. Here we demonstrate a statistical c…

  Authors: Paul H Lerou, Akiko Yabuuchi, Hongguang Huo, Ayumu Takeuchi, Jessica Shea, Tina Cimini, Tan A Ince, Elizabeth Ginsburg, Catherine Racowsky, George Q Daley

  Source: Nature biotechnology. 2008 Feb

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• Therapeutic potential of embryonic stem cells.

  Nearly 20 years after murine embryonic stem cells (mESC) were isolated, the first report of the derivation of human embryonic stem cells (hESC) in 199…

  Authors: Paul H Lerou, George Q Daley

  Source: Blood reviews. 2005 Nov

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• Generation of human-induced pluripotent stem cells.

  Pluripotent cells, such as embryonic stem cells, are invaluable tools for research and can potentially serve as a source of cell- and tissue-replaceme…

  Authors: In-Hyun Park, Paul H Lerou, Rui Zhao, Hongguang Huo, George Q Daley

  Source: Nature protocols. 2008

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• Derivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryos.

  Human embryonic stem (hES) cells are self-renewing, pluripotent cells that are valuable research tools and hold promise for use in regenerative medici…

  Authors: Paul H Lerou, Akiko Yabuuchi, Hongguang Huo, Justine D Miller, Leah F Boyer, Thorsten M Schlaeger, George Q Daley

  Source: Nature protocols. 2008

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