1 to 8 of 8 literature results

• HMGB1: guiding immunity from within.

  Two of the main challenges that eukaryotic multicellular organisms faced during evolution were to eliminate and replace dying cells and to cope with i…

  Authors: Ingrid E Dumitriu, Paramita Baruah, Angelo A Manfredi, Marco E Bianchi, Patrizia Rovere-Querini

  Source: Trends in immunology. 2005 Jul

  View Full Text

• C1q enhances IFN-gamma production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells.

  Dendritic cells (DCs) are known to produce C1q, the initiator of the classical complement pathway. We demonstrate that murine DCs deficient in C1q (C1…

  Authors: Paramita Baruah, Ingrid E Dumitriu, Talat H Malik, H Terence Cook, Julian Dyson, Diane Scott, Elizabeth Simpson, Marina Botto

  Source: Blood. 2009 Apr 9

  View Full Text

• The pattern recognition receptor PTX3 is recruited at the synapse between dying and dendritic cells, and edits the cross-presentation of self, viral, and tumor antigens.

  Pentraxins are soluble pattern recognition receptors with a dual role: protection against extracellular microbes and autoimmunity. The mechanisms by w…

  Authors: Paramita Baruah, Antonella Propato, Ingrid E Dumitriu, Patrizia Rovere-Querini, Vincenzo Russo, Raffaella Fontana, Daniele Accapezzato, Giuseppe Peri, Alberto Mantovani, Vincenzo Barnaba,…

  Source: Blood. 2006 Jan 1

  View Full Text

• The tissue pentraxin PTX3 limits C1q-mediated complement activation and phagocytosis of apoptotic cells by dendritic cells.

  Pentraxins (PTX) and complement belong to the humoral arm of the innate immune system and have essential functions in immune defense to microbes and i…

  Authors: Paramita Baruah, Ingrid E Dumitriu, Giuseppe Peri, Vincenzo Russo, Alberto Mantovani, Angelo A Manfredi, Patrizia Rovere-Querini

  Source: Journal of leukocyte biology. 2006 Jul

  View Full Text

• Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells.

  Dendritic cells (DC) are key components of innate and adaptive immune responses. Plasmacytoid DC (PDC) are a specialized DC subset that produce high a…

  Authors: Ingrid E Dumitriu, Paramita Baruah, Marco E Bianchi, Angelo A Manfredi, Patrizia Rovere-Querini

  Source: European journal of immunology. 2005 Jul

  View Full Text

• Innate responses to Aspergillus: role of C1q and pentraxin 3 in nasal polyposis.

  BACKGROUND: Pentraxin 3 (PTX3) and complement component C1q are humoral factors of innate immunity, produced at sites of inflammation, and are essenti…

  Authors: Paramita Baruah, Matteo Trimarchi, Ingrid E Dumitriu, Giacomo Dellantonio, Claudio Doglioni, Patrizia Rovere-Querini, Mario Bussi, Angelo A Manfredi

  Source: American journal of rhinology. 2007 Mar-Apr

  View Full Text

• Endoscopic management of inverted papillomas of the nose and paranasal sinuses.

  We performed endoscopic resection on six patients who had inverted papillomas of the nasal cavity. Disease was completely cleared in four patients aft…

  Authors: Paramita Baruah, Ramesh C Deka

  Source: Ear, nose, & throat journal. 2003 Apr

  View Full Text

• Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products.

  High mobility group box 1 (HMGB1) is an abundant and conserved nuclear protein that is released by necrotic cells and acts in the extracellular enviro…

  Authors: Ingrid E Dumitriu, Paramita Baruah, Barbara Valentinis, Reinhard E Voll, Martin Herrmann, Peter P Nawroth, Bernd Arnold, Marco E Bianchi, Angelo A Manfredi, Patrizia Rovere-Querini

  Source: Journal of immunology (Baltimore, Md. : 1950). 2005 Jun 15

  View Full Text