1 to 10 of 32 literature results

• Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.

  Spirometric measures of lung function are heritable traits that reflect respiratory health and predict morbidity and mortality. We meta-analyzed genom…

  Authors: Dana B Hancock, Mark Eijgelsheim, Jemma B Wilk, Sina A Gharib, Laura R Loehr, Kristin D Marciante, Nora Franceschini, Yannick M T A van Durme, Ting-Hsu Chen, R Graham Barr,…

  Source: Nature genetics. 2010 Jan

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• Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study.

  OBJECTIVE: Although variants in the transcription factor 7-like 2 (TCF7L2) gene are consistently associated with type 2 diabetes, large population-bas…

  Authors: Yu Yan, Kari E North, Christie M Ballantyne, Frederick L Brancati, Lloyd E Chambless, Nora Franceschini, Gerardo Heiss, Anna Kottgen, James S Pankow, Elizabeth Selvin,…

  Source: Diabetes. 2009 Jan

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• The effects of HIV type-1 viral suppression and non-viral factors on quantitative proteinuria in the highly active antiretroviral therapy era.

  BACKGROUND: Proteinuria is associated with progressive renal disease and overall mortality in HIV-infected patients; however, the prevalence and corre…

  Authors: Samir K Gupta, Marlene Smurzynski, Nora Franceschini, Ronald J Bosch, Lynda A Szczech, Robert C Kalayjian, AIDS Clinical Trials Group Longitudinal Linked Randomized Trials Study Team

  Source: Antiviral therapy. 2009

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• The association of the MYH9 gene and kidney outcomes in American Indians: the Strong Heart Family Study.

  Chronic kidney disease (CKD) is an important public health problem in American Indian populations. Recent research has identified associations of poly…

  Authors: Nora Franceschini, V Saroja Voruganti, Karin Haack, Laura Almasy, Sandy Laston, Harald H H Goring, Jason G Umans, Elisa T Lee, Lyle G Best, Richard R Fabsitz,…

  Source: Human genetics. 2010 Mar

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• Genotype-by-sex interaction on fasting insulin concentration: the HyperGEN study.

  Recent studies have demonstrated the importance of sex effects on the underlying genetic architecture of insulin-related traits. To explore sex-specif…

  Authors: Kari E North, Nora Franceschini, Ingrid B Borecki, C Charles Gu, Gerardo Heiss, Michael A Province, Donna K Arnett, Cora E Lewis, Michael B Miller, Richard H Myers,…

  Source: Diabetes. 2007 Jan

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• Genetic influence on variation in serum uric acid in American Indians: the strong heart family study.

  Hyperuricemia is associated with the metabolic syndrome, gout, renal and cardiovascular disease (CVD). American Indians have high rates of CVD and 25%…

  Authors: V Saroja Voruganti, Harald H H Göring, Amy Mottl, Nora Franceschini, Karin Haack, Sandra Laston, Laura Almasy, Richard R Fabsitz, Elisa T Lee, Lyle G Best,…

  Source: Human genetics. 2009 Nov

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• Linkage analysis of glomerular filtration rate in American Indians.

  American Indians have a disproportionately high rate of kidney disease likely due to a combination of environmental and genetic factors. We performed …

  Authors: Amy K Mottl, Suma Vupputuri, Shelley A Cole, Laura Almasy, Harald H H Göring, Vincent P Diego, Sandra Laston, Nora Franceschini, Nawar M Shara, Elisa T Lee,…

  Source: Kidney international. 2008 Nov

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• Incidence and etiology of acute renal failure among ambulatory HIV-infected patients.

  BACKGROUND: Acute renal failure (ARF) is a cause of renal dysfunction in human immunodeficiency virus (HIV)-infected patients. Its incidence and cause…

  Authors: Nora Franceschini, Sonia Napravnik, Joseph J Eron, Lynda A Szczech, William F Finn

  Source: Kidney international. 2005 Apr

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• A quantitative trait loci-specific gene-by-sex interaction on systolic blood pressure among American Indians: the Strong Heart Family Study.

  Age-adjusted systolic blood pressure is higher in males than females. Genetic factors may account for this sex-specific variation. To localize sex-spe…

  Authors: Nora Franceschini, Jean W MacCluer, Harald H H Göring, Shelley A Cole, Kathryn M Rose, Laura Almasy, Vincent Diego, Sandra Laston, Elisa T Lee, Barbara V Howard,…

  Source: Hypertension. 2006 Aug

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• The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study.

  BACKGROUND: Recent experimental evidence suggests that DNA damage and cell cycle regulatory proteins are involved in kidney injury and apoptosis. The …

  Authors: Nora Franceschini, Kari E North, Donna Arnett, James S Pankow, Jay H Chung, Lisa Baird, Mark F Leppert, John H Eckfeldt, Eric Boerwinkle, C Charles Gu,…

  Source: American journal of hypertension. 2009 May

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