1 to 10 of 26 literature results

• Localization of phospho-tyrosine489-beta-adducin immunoreactivity in the hypothalamic tanycytes and its involvement in energy homeostasis.

  beta-Adducin is a cytoskeletal protein that interacts with the actin filaments to suppress actin polymerization and facilitate actin-spectrin binding.…

  Authors: Hitoshi Gotoh, Akiko Okumura, Katsuya Nagai, Nobuaki Okumura

  Source: Brain research. 2008 Sep 4

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• Colocalization of a carnosine-splitting enzyme, tissue carnosinase (CN2)/cytosolic non-specific dipeptidase 2 (CNDP2), with histidine decarboxylase in the tuberomammillary nucleus of the hypothalamus.

  Carnosine is a naturally occurring dipeptide (beta-alanyl-l-histidine) present in mammalian tissues such as the brain and skeletal muscles. Carnosine …

  Authors: Hiroto Otani, Akiko Okumura, Katsuya Nagai, Nobuaki Okumura

  Source: Neuroscience letters. 2008 Nov 14

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• Proteomic analysis of slow- and fast-twitch skeletal muscles.

  Skeletal muscles are composed of slow- and fast-twitch muscle fibers, which have high potential in aerobic and anaerobic ATP production, respectively.…

  Authors: Nobuaki Okumura, Akiko Hashida-Okumura, Kanako Kita, Masami Matsubae, Toshiya Matsubara, Toshifumi Takao, Katsuya Nagai

  Source: Proteomics. 2005 Jul

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• Fyn-induced phosphorylation of beta-adducin at tyrosine 489 and its role in their subcellular localization.

  Fyn is a Src-family tyrosine kinase involved in neuronal development, transmission, and plasticity in mammalian central nervous system. We have previo…

  Authors: Hitoshi Gotoh, Nobuaki Okumura, Takeshi Yagi, Akiko Okumura, Takaki Shima, Katsuya Nagai

  Source: Biochemical and biophysical research communications. 2006 Jul 28

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• cGMP-dependent phosphorylation and degradation of myristoylated alanine-rich C-kinase substrate.

  In the mammalian brain, nitric oxide (NO) has been implicated in neuronal signal transmissions. NO stimulates guanylate cyclase to increase intracellu…

  Authors: Toshiya Matsubara, Nobuaki Okumura, Akiko Okumura, Katsuya Nagai

  Source: Biochemical and biophysical research communications. 2005 Jan 28

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• Nerve growth factor attenuates 2-deoxy-d-glucose-triggered endoplasmic reticulum stress-mediated apoptosis via enhanced expression of GRP78.

  The glucose analog 2-deoxy-d-glucose (2DG) depletes cells of glucose. Inhibition of glycosylation caused by glucose depletion induces endoplasmic reti…

  Authors: Soichiro Kishi, Koji Shimoke, Yosuke Nakatani, Takafumi Shimada, Nobuaki Okumura, Katsuya Nagai, Kazuo Shin-Ya, Toshihiko Ikeuchi

  Source: Neuroscience research. 2010 Jan

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• Identification and characterization of a mouse dipeptidase that hydrolyzes L-carnosine.

  L-Carnosine is a bioactive dipeptide present in mammalian tissues including the central nervous system. We have recently shown that L-carnosine is inv…

  Authors: Hiroto Otani, Nobuaki Okumura, Akiko Hashida-Okumura, Katsuya Nagai

  Source: Journal of biochemistry. 2005 Feb

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• Evidence for phosphorylation of rat liver glucose-regulated protein 58, GRP58/ERp57/ER-60, induced by fasting and leptin.

  Glucose-regulated protein 58 (GRP58)-like immunoreactivity in rat liver obtained in the evening or after fasting underwent an electrophoretic band-shi…

  Authors: Kanako Kita, Nobuaki Okumura, Toshifumi Takao, Makoto Watanabe, Toshiya Matsubara, Osamu Nishimura, Katsuya Nagai

  Source: FEBS letters. 2006 Jan 9

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• Effects of central injection of L-carnosine on sympathetic nerve activity innervating brown adipose tissue and body temperature in rats.

  In the present study, using urethane-anesthetized rats, we examined the effects of intralateral cerebral ventricular (LCV) injection of various doses …

  Authors: Mamoru Tanida, Hitoshi Gotoh, Hiroyuki Taniguchi, Hiroto Otani, Jiao Shen, Takuo Nakamura, Nobuo Tsuruoka, Yoshinobu Kiso, Nobuaki Okumura, Katsuya Nagai

  Source: Regulatory peptides. 2007 Dec 4

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• Tyrosine phosphorylation of BIT on photic stimulation in the rat retina.

  BIT is a transmembrane glycoprotein with three immunoglobulin-like domains in its extracellular region and tyrosine phosphorylation sites in its cytos…

  Authors: Juri Hamada, Nobuaki Okumura, Miho Inagaki, Hiroyuki Taniguchi, Yasukazu Nakahata, Shin-ichiro Sano, Katsuya Nagai

  Source: FEBS letters. 2004 Jan 16

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