1 to 10 of 11 literature results

• Wnt pathway inhibitors are strongly down-regulated in pituitary tumors.

  The etiology of sporadic pituitary tumors is currently unknown. The Wnt pathways have been implicated in the pathogenesis of a variety of human tumors…

  Authors: Marianne S Elston, Anthony J Gill, John V Conaglen, Adele Clarkson, Janet M Shaw, Andrew J J Law, Raymond J Cook, Nicholas S Little, Roderick J Clifton-Bligh, Bruce G Robinson,…

  Source: Endocrinology. 2008 Mar

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• Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours.

  CONTEXT: Recent case reports detail the successful use of temozolomide in the management of aggressive pituitary tumours. O(6)-methylguanine-DNA methy…

  Authors: Ann I McCormack, Kerrie L McDonald, Anthony J Gill, Susan J Clark, Morton G Burt, Kirsten A Campbell, Wilton J Braund, Nicholas S Little, Raymond J Cook, Ashley B Grossman,…

  Source: Clinical endocrinology. 2009 Aug

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• IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients.

  Clinical treatment decisions and the survival outcomes of patients with gliomas are directly impacted by accurate tumor classification. New and more r…

  Authors: Kerrie L McDonald, Maree G O'Sullivan, Jonathon F Parkinson, Janet M Shaw, Cathy A Payne, Janice M Brewer, Lawrence Young, Dianne J Reader, Helen T Wheeler, Raymond J Cook,…

  Source: Journal of neuropathology and experimental neurology. 2007 May

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• Loss of prostaglandin D2 synthase: a key molecular event in the transition of a low-grade astrocytoma to an anaplastic astrocytoma.

  Reduction in the mRNA and protein expression of lipocalin-like prostaglandin D(2) (PGD(2)) synthase (PGDS), the main arachidonic acid metabolite produ…

  Authors: Cathy A Payne, Sanaz Maleki, Marinella Messina, Maree G O'Sullivan, Glenn Stone, Nathan R Hall, Jonathon F Parkinson, Helen R Wheeler, Raymond J Cook, Michael T Biggs,…

  Source: Molecular cancer therapeutics. 2008 Oct

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• Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma.

  Methylation of the promoter region of the O ( 6 ) -methylguanine-DNA methyltransferase (MGMT) gene is known to be predictive of response to temozolomi…

  Authors: Jonathon F Parkinson, Helen R Wheeler, Adele Clarkson, Catriona A McKenzie, Michael T Biggs, Nicholas S Little, Raymond J Cook, Marinella Messina, Bruce G Robinson, Kerrie L McDonald

  Source: Journal of neuro-oncology. 2008 Mar

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• Chiari malformation, cervical disc prolapse and syringomyelia--always think twice.

  We present the case of a 36-year-old man with neck pain and parasthesia of both upper limbs. Magnetic resonance imaging demonstrated a cervical disc p…

  Authors: Jonathon R Ball, Nicholas S Little

  Source: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2008 Apr

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• The presence of necrosis and/or microvascular proliferation does not influence survival of patients with anaplastic oligodendroglial tumours: review of 98 patients.

  Accurate prognosis for patients with anaplastic oligodendroglial gliomas is increasingly difficult to make. Characterisation of these tumours remains …

  Authors: Sarah F Smith, Judy M Simpson, Janice A Brewer, Lali H S Sekhon, Michael T Biggs, Raymond J Cook, Nicholas S Little

  Source: Journal of neuro-oncology. 2006 Oct

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• Delayed hemorrhage following resection of an arteriovenous malformation in the brain.

  OBJECT: Between 1989 and 2002 the authors treated 416 cases of angiographically confirmed arteriovenous malformations (AVMs) of the brain. METHODS: Th…

  Authors: Michael K Morgan, Mark Winder, Nicholas S Little, Simon Finfer, Elizabeth Ritson

  Source: Journal of neurosurgery. 2003 Dec

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• Nuclear accumulation of e-cadherin correlates with loss of cytoplasmic membrane staining and invasion in pituitary adenomas.

  CONTEXT: Loss of the cell adhesion protein E-cadherin is associated with invasion and metastasis in a number of malignancies. Recent studies have high…

  Authors: Marianne S Elston, Anthony J Gill, John V Conaglen, Adele Clarkson, Raymond J Cook, Nicholas S Little, Bruce G Robinson, Roderick J Clifton-Bligh, Kerrie L McDonald

  Source: The Journal of clinical endocrinology and metabolism. 2009 Apr

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• Headache of a diagnosis: frontotemporal pain and inflammation associated with osteolysis.

  A 62-year-old woman presented with left frontotemporal pain, scalp tenderness and raised levels of inflammatory markers. Temporal arteritis was consid…

  Authors: Lyndal J Tacon, Jonathon F Parkinson, Bernard J Hudson, Janice M Brewer, Nicholas S Little, Roderick J Clifton-Bligh

  Source: The Medical journal of Australia. 2008 Nov 17

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