1 to 10 of 18 literature results

• Multiple ADH genes are associated with upper aerodigestive cancers.

  Alcohol is an important risk factor for upper aerodigestive cancers and is principally metabolized by alcohol dehydrogenase (ADH) enzymes. We have inv…

  Authors: Mia Hashibe, James D McKay, Maria Paula Curado, Jose Carlos Oliveira, Sergio Koifman, Rosalina Koifman, David Zaridze, Oxana Shangina, Victor Wünsch-Filho, Jose Eluf-Neto,…

  Source: Nature genetics. 2008 Jun

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• A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.

  Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually. To identify genetic factors that modify disease …

  Authors: Rayjean J Hung, James D McKay, Valerie Gaborieau, Paolo Boffetta, Mia Hashibe, David Zaridze, Anush Mukeria, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai,…

  Source: Nature. 2008 Apr 3

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• Lung cancer susceptibility locus at 5p15.33.

  We carried out a genome-wide association study of lung cancer (3,259 cases and 4,159 controls), followed by replication in 2,899 cases and 5,573 contr…

  Authors: James D McKay, Rayjean J Hung, Valerie Gaborieau, Paolo Boffetta, Amelie Chabrier, Graham Byrnes, David Zaridze, Anush Mukeria, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska,…

  Source: Nature genetics. 2008 Dec

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• Effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach.

  Whether consumption of cruciferous vegetables protects against lung cancer is unclear, largely because of potential confounding factors. We therefore …

  Authors: Paul Brennan, Charles C Hsu, Norman Moullan, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, David Zaridze, Peter Rudnai, Eleonora Fabianova, Dana Mates, Vladimir Bencko,…

  Source: Lancet. 2005 Oct 29-Nov 4

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• Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium.

  BACKGROUND: At least 75% of head and neck cancers are attributable to a combination of cigarette smoking and alcohol drinking. A precise understanding…

  Authors: Mia Hashibe, Paul Brennan, Simone Benhamou, Xavier Castellsague, Chu Chen, Maria Paula Curado, Luigino Dal Maso, Alexander W Daudt, Eleonora Fabianova, Leticia Fernandez,…

  Source: Journal of the National Cancer Institute. 2007 May 16

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• Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk.

  Lipid peroxidation is considered a unifying mechanistic pathway through which known risk factors induce renal cell carcinoma (RCC). We hypothesized th…

  Authors: Lee E Moore, Paul Brennan, Sara Karami, Idan Menashe, Sonja I Berndt, Linda M Dong, Allison Meisner, Meredith Yeager, Stephen Chanock, Joanne Colt,…

  Source: Cancer research. 2009 Oct 15

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• Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: case control study.

  CHEK2 is a key cell cycle control gene encoding a pluripotent kinase that can cause arrest or apoptosis in response to unrepaired DNA damage. We repor…

  Authors: Paul Brennan, James McKay, Lee Moore, David Zaridze, Anush Mukeria, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai, Eleonora Fabianova, Dana Mates,…

  Source: Human molecular genetics. 2007 Aug 1

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• DNA repair and cell cycle control genes and the risk of young-onset lung cancer.

  Exposure to tobacco smoke and to mutagenic xenobiotics can cause various types of DNA damage in lung cells, which, if not corrected by DNA repair syst…

  Authors: Stefano Landi, Federica Gemignani, Federico Canzian, Valérie Gaborieau, Roberto Barale, Debora Landi, Neonilia Szeszenia-Dabrowska, David Zaridze, Jolanta Lissowska, Peter Rudnai,…

  Source: Cancer research. 2006 Nov 15

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• Dietary risk factors for kidney cancer in Eastern and Central Europe.

  The authors examined the role of diet in the high-risk population of Central Europe among 1,065 incident kidney cancer cases and 1,509 controls in Rus…

  Authors: Charles C Hsu, Wong-Ho Chow, Paolo Boffetta, Lee Moore, David Zaridze, Anush Moukeria, Vladimir Janout, Helena Kollarova, Vladimir Bencko, Marie Navratilova,…

  Source: American journal of epidemiology. 2007 Jul 1

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• Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE Consortium.

  The authors pooled data from 15 case-control studies of head and neck cancer (9,107 cases, 14,219 controls) to investigate the independent association…

  Authors: Mark P Purdue, Mia Hashibe, Julien Berthiller, Carlo La Vecchia, Luigino Dal Maso, Rolando Herrero, Silvia Franceschi, Xavier Castellsague, Qingyi Wei, Erich M Sturgis,…

  Source: American journal of epidemiology. 2009 Jan 15

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