1 to 10 of 21 literature results

• Principal components analysis corrects for stratification in genome-wide association studies.

  Population stratification--allele frequency differences between cases and controls due to systematic ancestry differences-can cause spurious associati…

  Authors: Alkes L Price, Nick J Patterson, Robert M Plenge, Michael E Weinblatt, Nancy A Shadick, David Reich

  Source: Nature genetics. 2006 Aug

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• De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot.

  Tetralogy of Fallot (TOF), the most common severe congenital heart malformation, occurs sporadically, without other anomaly, and from unknown cause in…

  Authors: Steven C Greenway, Alexandre C Pereira, Jennifer C Lin, Steven R DePalma, Samuel J Israel, Sonia M Mesquita, Emel Ergul, Jessie H Conta, Joshua M Korn, Steven A McCarroll,…

  Source: Nature genetics. 2009 Aug

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• Vitamin E in the primary prevention of rheumatoid arthritis: the Women's Health Study.

  OBJECTIVE: Vitamin E supplements may reduce the risk of developing rheumatoid arthritis (RA) through antioxidant effects. Although previous observatio…

  Authors: Elizabeth W Karlson, Nancy A Shadick, Nancy R Cook, Julie E Buring, I-Min Lee

  Source: Arthritis and rheumatism. 2008 Nov 15

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• Common variants at CD40 and other loci confer risk of rheumatoid arthritis.

  To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-analysis of two published genome-wide association (GWA) studie…

  Authors: Soumya Raychaudhuri, Elaine F Remmers, Annette T Lee, Rachel Hackett, Candace Guiducci, Noël P Burtt, Lauren Gianniny, Benjamin D Korman, Leonid Padyukov, Fina A S Kurreeman,…

  Source: Nature genetics. 2008 Oct

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• Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.

  To identify susceptibility alleles associated with rheumatoid arthritis, we genotyped 397 individuals with rheumatoid arthritis for 116,204 SNPs and c…

  Authors: Robert M Plenge, Chris Cotsapas, Leela Davies, Alkes L Price, Paul I W de Bakker, Julian Maller, Itsik Pe'er, Noel P Burtt, Brendan Blumenstiel, Matt DeFelice,…

  Source: Nature genetics. 2007 Dec

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• Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.

  To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs from 179 independent loci with P < 0.001 in a published meta-…

  Authors: Soumya Raychaudhuri, Brian P Thomson, Elaine F Remmers, Stephen Eyre, Anne Hinks, Candace Guiducci, Joseph J Catanese, Gang Xie, Eli A Stahl, Robert Chen,…

  Source: Nature genetics. 2009 Dec

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• Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies.

  OBJECTIVE: To examine the association of biomarkers of inflammation with preclinical rheumatoid arthritis (RA). METHODS: A nested case-control study w…

  Authors: Elizabeth W Karlson, Lori B Chibnik, Shelley S Tworoger, I-Min Lee, Julie E Buring, Nancy A Shadick, Joann E Manson, Karen H Costenbader

  Source: Arthritis and rheumatism. 2009 Mar

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• Outcomes in rheumatoid arthritis: incorporating the patient perspective.

  PURPOSE OF REVIEW: As biologics have improved the prognosis for rheumatoid arthritis, the prioritization of outcomes has shifted. Methods of quantifyi…

  Authors: Jenny E Heller, Nancy A Shadick

  Source: Current opinion in rheumatology. 2007 Mar

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• C-reactive protein in the prediction of rheumatoid arthritis in women.

  BACKGROUND: The purpose of this study was to examine whether levels of C-reactive protein (CRP), a sensitive marker of disease activity in rheumatoid …

  Authors: Nancy A Shadick, Nancy R Cook, Elizabeth W Karlson, Paul M Ridker, Nancy E Maher, Joann E Manson, Julie E Buring, I-Min Lee

  Source: Archives of internal medicine. 2006 Dec 11-25

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• The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28.

  The objective of this work was to assess the convergent validity of a previously developed rheumatoid arthritis medical records-based index of severit…

  Authors: Masayo Sato, Sebastian Schneeweiss, Richard Scranton, Jeffrey N Katz, Michael E Weinblatt, Jerry Avorn, Gladys Ting, Nancy A Shadick, Daniel H Solomon

  Source: Arthritis research & therapy. 2006

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