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Membrane proteins are key targets for pharmacological intervention because they are vital for cellular function. Here, we analyze recent progress made…
Authors: Daniel J Müller, Nan Wu, Krzysztof Palczewski
Source: Pharmacological reviews. 2008 Mar
View Free Full TextIntracellular heme levels must be tightly regulated to maintain proper mitochondrial respiration while minimizing toxicity, but the homeostatic mechan…
Authors: Nan Wu, Lei Yin, Elyisha A Hanniman, Shree Joshi, Mitchell A Lazar
Source: Genes & development. 2009 Sep 15
View Free Full TextAlthough the BCR/ABL tyrosine kinase inhibitor imatinib is highly effective for treatment of chronic myelogenous leukemia and Philadelphia chromosome-…
Authors: Tetsuya Kurosu, Manabu Ohki, Nan Wu, Hiroyuki Kagechika, Osamu Miura
Source: Cancer research. 2009 May 1
View Full Text1,3-Bis-[2-hydroxy-5-(trifluoromethyl)phenyl]urea (NS1643) is reported to be an activator of human ether-à-go-go-related gene current. However, it rem…
Authors: Sheng-Nan Wu, Hsung Peng, Bing-Shuo Chen, Ya-Jean Wang, Pei-Yu Wu, Ming-Wei Lin
Source: Molecular pharmacology. 2008 Dec
View Full TextThe effects of rottlerin, a known inhibitor of protein kinase C-delta activation, on ion currents were investigated in pituitary tumor (GH3) cells. Ro…
Authors: Sheng-Nan Wu, Ya-Jean Wang, Ming-Wei Lin
Source: Journal of cellular physiology. 2007 Mar
View Full TextHistone variants and their modification have significant roles in many cellular processes. In this study, we identified and characterized the histone …
Authors: Nan Wu, Hua-Mei Yue, Bo Chen, Jian-Fang Gui
Source: Biology of reproduction. 2009 Aug
View Full TextThis paper presents a novel Fabry-Perot (FP) optical fiber pressure/acoustic sensor. It consists of two V-shaped grooves having different sized widths…
Authors: Wenhui Wang, Nan Wu, Ye Tian, Xingwei Wang, Christopher Niezrecki, Julie Chen
Source: Optics express. 2009 Sep 14
View Full TextThe helicase domain of dengue virus NS3 protein (DENV NS3H) contains RNA-stimulated nucleoside triphosphatase (NTPase), ATPase/helicase, and RNA 5'-tr…
Authors: Chun-Chung Wang, Zhi-Shun Huang, Pei-Ling Chiang, Chien-Tsun Chen, Huey-Nan Wu
Source: FEBS letters. 2009 Feb 18
View Full TextThe electron density and the electrostatic potential (ESP) distributions of estrone have been determined using X-ray diffraction analysis and compared…
Authors: Elizabeth A Zhurova, Chérif F Matta, Nan Wu, Vladimir V Zhurov, A Alan Pinkerton
Source: Journal of the American Chemical Society. 2006 Jul 12
View Full TextPriB is a primosomal protein required for replication restart in Escherichia coli. PriB stimulates PriA helicase activity via interaction with single-…
Authors: Cheng-Yang Huang, Che-Hsiung Hsu, Yuh-Ju Sun, Huey-Nan Wu, Chwan-Deng Hsiao
Source: Nucleic acids research. 2006
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