1 to 4 of 4 literature results

• Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia.

  Malignant hyperthermia (MH) is a potentially fatal, inherited skeletal muscle disorder in humans and pigs that is caused by abnormal regulation of Ca2…

  Authors: D R Laver, V J Owen, P R Junankar, N L Taske, A F Dulhunty, G D Lamb

  Source: Biophysical journal. 1997 Oct

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• Exclusion of defects in the skeletal muscle specific regions of the DHPR alpha 1 subunit as frequent causes of malignant hyperthermia.

  The molecular defect predisposing to the majority of malignant hyperthermia (MH) cases is unknown, although various point mutations in the ryanodine r…

  Authors: R O O'Brien, N L Taske, P M Hansbro, K I Matthaei, S P Hogan, M A Denborough, P S Foster

  Source: Journal of medical genetics. 1995 Nov

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• Reduced Mg2+ inhibition of Ca2+ release in muscle fibers of pigs susceptible to malignant hyperthermia.

  The inhibitory effect of myoplasmic Mg2+ on Ca2+ release from the sarcoplasmic reticulum (SR) was examined in mechanically skinned skeletal muscle fib…

  Authors: V J Owen, N L Taske, G D Lamb

  Source: The American journal of physiology. 1997 Jan

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• Molecular cloning of the cDNA encoding human skeletal muscle triadin and its localisation to chromosome 6q22-6q23.

  We have cloned and sequenced the cDNA encoding triadin, a junctional terminal cisternae protein from human skeletal muscle. The cDNA, 2941 base pairs …

  Authors: N L Taske, H J Eyre, R O O'Brien, G R Sutherland, M A Denborough, P S Foster

  Source: European journal of biochemistry / FEBS. 1995 Oct 1

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