10 literature results

• TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation.

  Dendritic cells (DCs) are professional antigen-presenting cells that have the ability to sense infection and tissue stress, sample and present antigen…

  Authors: Yong-Jun Liu, Vasilli Soumelis, Norihiko Watanabe, Tomoki Ito, Yui-Hsi Wang, Rene de Waal Malefyt, Miyuki Omori, Baohua Zhou, Steven F Ziegler

  Source: Annual review of immunology. 2007

  View Full Text

• Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development.

  The cytokine thymic stromal lymphopoietin (TSLP) drives immature B cell development in vitro and may regulate T helper type 2 responses. Here we analy…

  Authors: Alexander Astrakhan, Miyuki Omori, Thuc Nguyen, Shirly Becker-Herman, Masanori Iseki, Theingi Aye, Kelly Hudkins, James Dooley, Andrew Farr, Charles E Alpers,…

  Source: Nature immunology. 2007 May

  View Full Text

• CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA.

  Chromatin remodeling of type 2 cytokine gene loci occurs during differentiation of naive CD4 and CD8 T cells into type 2 helper (Th2) and cytotoxic (T…

  Authors: Miyuki Omori, Masakatsu Yamashita, Masamichi Inami, Maki Ukai-Tadenuma, Motoko Kimura, Yukiko Nigo, Hiroyuki Hosokawa, Akihiro Hasegawa, Masaru Taniguchi, Toshinori Nakayama

  Source: Immunity. 2003 Aug

  View Full Text

• Induction of IL-4 expression in CD4(+) T cells by thymic stromal lymphopoietin.

  The cytokine thymic stromal lymphopoietin (TSLP) has been implicated in the development and progression of allergic inflammation in both humans and mi…

  Authors: Miyuki Omori, Steven Ziegler

  Source: Journal of immunology (Baltimore, Md. : 1950). 2007 Feb 1

  View Full Text

• Methods for detection, isolation and culture of mouse and human invariant NKT cells.

  This protocol describes methods to identify, purify and culture CD1d restricted invariant natural killer T (iNKT) cells from mouse tissue or human blo…

  Authors: Hiroshi Watarai, Ryusuke Nakagawa, Miyuki Omori-Miyake, Nyambayar Dashtsoodol, Masaru Taniguchi

  Source: Nature protocols. 2008

  View Full Text

• T(h)1/T(h)2 cell differentiation of developing CD4 single-positive thymocytes.

  In this study we investigate the stage at which developing T cells in the thymus acquire the ability to differentiate into T(h)1 and T(h)2 cells. We a…

  Authors: Emiko Kikkawa, Masakatsu Yamashita, Motoko Kimura, Miyuki Omori, Kaoru Sugaya, Chiori Shimizu, Takuo Katsumoto, Masahiko Ikekita, Masaru Taniguchi, Toshinori Nakayama

  Source: International immunology. 2002 Aug

  View Full Text

• Intradermal administration of thymic stromal lymphopoietin induces a T cell- and eosinophil-dependent systemic Th2 inflammatory response.

  The epithelial-derived cytokine thymic stromal lymphopoietin (TSLP) is sufficient to induce asthma or atopic dermatitis-like phenotypes when selective…

  Authors: Heidi K Jessup, Avery W Brewer, Miyuki Omori, Erika A Rickel, Alison L Budelsky, Bo-Rin Park Yoon, Steven F Ziegler, Michael R Comeau

  Source: Journal of immunology (Baltimore, Md. : 1950). 2008 Sep 15

  View Full Text

• Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin.

  The cytokine thymic stromal lymphopoietin (TSLP) has recently been implicated in the pathogenesis of atopic dermatitis (AD) and other allergic disease…

  Authors: Jane Yoo, Miyuki Omori, Dora Gyarmati, Baohua Zhou, Theingi Aye, Avery Brewer, Michael R Comeau, Daniel J Campbell, Steven F Ziegler

  Source: The Journal of experimental medicine. 2005 Aug 15

  View Free Full Text

• STAT6-dependent differentiation and production of IL-5 and IL-13 in murine NK2 cells.

  NK cells differentiate into either NK1 or NK2 cells that produce IFN-gamma or IL-5 and IL-13, respectively. Little is known, however, about the molecu…

  Authors: Takuo Katsumoto, Motoko Kimura, Masakatsu Yamashita, Hiroyuki Hosokawa, Kahoko Hashimoto, Akihiro Hasegawa, Miyuki Omori, Takeshi Miyamoto, Masaru Taniguchi, Toshinori Nakayama

  Source: Journal of immunology (Baltimore, Md. : 1950). 2004 Oct 15

  View Full Text

• Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus.

  Differentiation of naive CD4 T cells into type 2 helper (Th2) cells is accompanied by chromatin remodeling of Th2 cytokine gene loci. Hyperacetylation…

  Authors: Masakatsu Yamashita, Maki Ukai-Tadenuma, Motoko Kimura, Miyuki Omori, Masamichi Inami, Masaru Taniguchi, Toshinori Nakayama

  Source: The Journal of biological chemistry. 2002 Nov 1

  View Full Text