1 to 10 of 92 literature results

• Cluster analysis and clinical asthma phenotypes.

  RATIONALE: Heterogeneity in asthma expression is multidimensional, including variability in clinical, physiologic, and pathologic parameters. Classifi…

  Authors: Pranab Haldar, Ian D Pavord, Dominic E Shaw, Michael A Berry, Michael Thomas, Christopher E Brightling, Andrew J Wardlaw, Ruth H Green

  Source: American journal of respiratory and critical care medicine. 2008 Aug 1

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• Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint.

  Beta-catenin has been implicated in thymocyte development because of its function as a coactivator of Tcf/LEF-family transcription factors. Previously…

  Authors: Toru Fukushima, Juan M Zapata, Netai C Singha, Michael Thomas, Christina L Kress, Maryla Krajewska, Stan Krajewski, Ze'ev Ronai, John C Reed, Shu-Ichi Matsuzawa

  Source: Immunity. 2006 Jan

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• The predominant role of coordination number in potassium channel selectivity.

  Potassium channels are exquisitely selective, allowing K+ to pass across cell membranes while blocking other ion types. Here we demonstrate that the n…

  Authors: Michael Thomas, Dylan Jayatilaka, Ben Corry

  Source: Biophysical journal. 2007 Oct 15

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• Supervised short-term nutrition and exercise promotes weight loss in overweight and obese patients with polycystic ovary syndrome.

  Thirty-two mid-reproductive-aged overweight and obese patients with polycystic ovary syndrome, most of whom had never exercised regularly, lost 3% to …

  Authors: Mira Aubuchon, Neil Laughbaum, Amy Poetker, Daniel Williams, Michael Thomas

  Source: Fertility and sterility. 2009 Apr

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• Daxx represses expression of a subset of antiapoptotic genes regulated by nuclear factor-kappaB.

  Daxx is a nuclear protein that localizes to PML oncogenic domains, sensitizes cells to apoptosis, and functions as a transcriptional repressor. We fou…

  Authors: Rhonda Croxton, Lorena A Puto, Ian de Belle, Michael Thomas, Seiji Torii, Farid Hanaii, Michael Cuddy, John C Reed

  Source: Cancer research. 2006 Sep 15

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• Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner.

  CDC are exotoxins secreted by many Gram-positive bacteria that bind cholesterol and oligomerize to form pores in eukaryotic cell membranes. We demonst…

  Authors: Jessica Chu, L Michael Thomas, Simon C Watkins, Luigi Franchi, Gabriel Núñez, Russell D Salter

  Source: Journal of leukocyte biology. 2009 Nov

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• Harvesting waste thermal energy using a carbon-nanotube-based thermo-electrochemical cell.

  Low efficiencies and costly electrode materials have limited harvesting of thermal energy as electrical energy using thermo-electrochemical cells (or …

  Authors: Renchong Hu, Baratunde A Cola, Nanda Haram, Joseph N Barisci, Sergey Lee, Stephanie Stoughton, Gordon Wallace, Chee Too, Michael Thomas, Adrian Gestos,…

  Source: Nano letters. 2010 Mar 10

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• BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress.

  Bax inhibitor-1 (BI-1) is an evolutionarily conserved endoplasmic reticulum (ER) protein that suppresses cell death in both animal and plant cells. We…

  Authors: Han-Jung Chae, Hyung-Ryong Kim, Chunyan Xu, Beatrice Bailly-Maitre, Maryla Krajewska, Stan Krajewski, Steven Banares, Janice Cui, Murat Digicaylioglu, Ning Ke,…

  Source: Molecular cell. 2004 Aug 13

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• Effects of polycystic ovarian syndrome on in vitro fertilization-embryo transfer outcomes are influenced by body mass index.

  OBJECTIVE: To determine whether polycystic ovary syndrome (PCOS) adversely impacts IVF-embryo transfer outcomes in obese compared to lean patients. DE…

  Authors: Betsy McCormick, Michael Thomas, Rose Maxwell, Daniel Williams, Mira Aubuchon

  Source: Fertility and sterility. 2008 Dec

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• Eosinophils induce DC maturation, regulating immunity.

  There are increased eosinophils in tumors, and they are generally associated with a good prognosis, whereas their presence in rejecting allografts is …

  Authors: Ramin Lotfi, Michael Thomas Lotze

  Source: Journal of leukocyte biology. 2008 Mar

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