1 to 10 of 45 literature results

• An amino acid shuffle activates mTORC1.

  The mammalian target of rapamycin complex 1 (mTORC1), which promotes cell growth, is regulated by specific nutrients such as the amino acid leucine. I…

  Authors: Adiel Cohen, Michael N Hall

  Source: Cell. 2009 Feb 6

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• mTOR and the control of whole body metabolism.

  Mammalian Target of Rapamycin (mTOR) is a highly conserved protein kinase that functions as part of two distinct multiprotein complexes to regulate gr…

  Authors: Pazit Polak, Michael N Hall

  Source: Current opinion in cell biology. 2009 Apr

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• TOR signaling in invertebrates.

  The Target of Rapamycin (TOR), a protein kinase, is the central node of a highly conserved signaling network that regulates cell growth in response to…

  Authors: Alexandre Soulard, Adiel Cohen, Michael N Hall

  Source: Current opinion in cell biology. 2009 Dec

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• TOR complex 2: a signaling pathway of its own.

  Research on TOR has grown exponentially during the last decade, generating a complex model of the TOR signaling network. Rapamycin treatment provides …

  Authors: Nadine Cybulski, Michael N Hall

  Source: Trends in biochemical sciences. 2009 Dec

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• TOR signaling in growth and metabolism.

  The target of rapamycin (TOR) is a conserved Ser/Thr kinase that regulates cell growth and metabolism in response to environmental cues. Here, highlig…

  Authors: Stephan Wullschleger, Robbie Loewith, Michael N Hall

  Source: Cell. 2006 Feb 10

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• Signal transduction: Linking nutrients to growth.

  Authors: Vittoria Zinzalla, Michael N Hall

  Source: Nature. 2008 Jul 17

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• mTORC2 Caught in a SINful Akt.

  The target of rapamycin (TOR), a central controller of cell growth, is found in two distinct, highly conserved multiprotein complexes. Three recent pa…

  Authors: Pazit Polak, Michael N Hall

  Source: Developmental cell. 2006 Oct

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• TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.

  The regulation of ribosome biogenesis in response to environmental conditions is a key aspect of cell growth control. Ribosomal protein (RP) genes are…

  Authors: Dietmar E Martin, Alexandre Soulard, Michael N Hall

  Source: Cell. 2004 Dec 29

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• The expanding TOR signaling network.

  Cell growth (increase in cell mass or size) is tightly coupled to nutrient availability, growth factors and the energy status of the cell. The target …

  Authors: Dietmar E Martin, Michael N Hall

  Source: Current opinion in cell biology. 2005 Apr

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• SnapShot: mTOR signaling.

  Authors: Alexandre Soulard, Michael N Hall

  Source: Cell. 2007 Apr 20

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