1 to 10 of 12 literature results

• Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1.

  Endometriosis is characterized by endometrial tissue growth outside the uterus, due primarily to survival, proliferation, and neoangiogenesis of eutop…

  Authors: Michael C Velarde, Lusine Aghajanova, Camran R Nezhat, Linda C Giudice

  Source: Endocrinology. 2009 Oct

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• The progesterone receptor coactivator Hic-5 is involved in the pathophysiology of endometriosis.

  Endometriosis is an estrogen-dependent disorder primarily associated with pelvic pain and infertility in up to 10% of women of reproductive age. Recen…

  Authors: Lusine Aghajanova, Michael C Velarde, Linda C Giudice

  Source: Endocrinology. 2009 Aug

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• Delayed parturition and altered myometrial progesterone receptor isoform A expression in mice null for Krüppel-like factor 9.

  Preterm and delayed labor conditions are devastating health problems with currently unknown etiologies. We previously showed that the transcription fa…

  Authors: Zhaoyang Zeng, Michael C Velarde, Frank A Simmen, Rosalia C M Simmen

  Source: Biology of reproduction. 2008 Jun

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• Altered gene expression profiling in endometrium: evidence for progesterone resistance.

  Progesterone plays an important role in regulating multiple events in the uterus. It controls endometrial proliferation and differentiation, which are…

  Authors: Lusine Aghajanova, Michael C Velarde, Linda C Giudice

  Source: Seminars in reproductive medicine. 2010 Jan

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• Progesterone receptor transactivation of the secretory leukocyte protease inhibitor gene in Ishikawa endometrial epithelial cells involves recruitment of Krüppel-like factor 9/basic transcription element binding protein-1.

  Progesterone receptor (PR), a ligand-inducible transcription factor, mediates the physiological actions of progesterone (P) through two distinct isofo…

  Authors: Michael C Velarde, Mary Iruthayanathan, Renea R Eason, Daying Zhang, Frank A Simmen, Rosalia C M Simmen

  Source: Endocrinology. 2006 Apr

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• Null mutation of Kruppel-like factor9/basic transcription element binding protein-1 alters peri-implantation uterine development in mice.

  Female mice null for the basic transcription element binding protein-1 (Bteb1) gene have reduced numbers of implanting embryos. We hypothesized that t…

  Authors: Michael C Velarde, Yan Geng, Renea R Eason, Frank A Simmen, Rosalia C M Simmen

  Source: Biology of reproduction. 2005 Sep

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• The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN.

  The isoflavone genistein (GEN), a biologically active component of soy foods, is associated with reduced breast cancer risk in women who consume soy-r…

  Authors: Bhuvanesh Dave, Renea R Eason, S Renée Till, Yan Geng, Michael C Velarde, Thomas M Badger, Rosalia C M Simmen

  Source: Carcinogenesis. 2005 Oct

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• Inhibition of NMU-induced mammary tumorigenesis by dietary soy.

  We previously demonstrated that female Sprague-Dawley rats fed AIN-93G diets containing soy protein isolate (SPI+) had lower DMBA-induced mammary tumo…

  Authors: Rosalia C M Simmen, Renea R Eason, S Reneé Till, Leon Chatman, Michael C Velarde, Yan Geng, Sohelia Korourian, Thomas M Badger

  Source: Cancer letters. 2005 Jun 16

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• Kruppel-like factor 9 is a negative regulator of ligand-dependent estrogen receptor alpha signaling in Ishikawa endometrial adenocarcinoma cells.

  Estrogen and progesterone, acting through their respective receptors and other nuclear proteins, exhibit opposing activities in target cells. We previ…

  Authors: Michael C Velarde, Zhaoyang Zeng, Jennelle R McQuown, Frank A Simmen, Rosalia C M Simmen

  Source: Molecular endocrinology (Baltimore, Md.). 2007 Dec

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• Dysregulation of intestinal crypt cell proliferation and villus cell migration in mice lacking Kruppel-like factor 9.

  Krüppel-like factor 9 (Klf9), a zinc-finger transcription factor, is implicated in the control of cell proliferation, cell differentiation, and cell f…

  Authors: Frank A Simmen, Rijin Xiao, Michael C Velarde, Rachel D Nicholson, Margaret T Bowman, Yoshiaki Fujii-Kuriyama, S Paul Oh, Rosalia C M Simmen

  Source: American journal of physiology. Gastrointestinal and liver physiology. 2007 Jun

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