1 to 10 of 39 literature results

• Renal aplasia in humans is associated with RET mutations.

  In animal models, kidney formation is known to be controlled by the proteins RET, GDNF, and GFRA1; however, no human studies to date have shown an ass…

  Authors: Michael A Skinner, Shawn D Safford, Justin G Reeves, Margaret E Jackson, Alex J Freemerman

  Source: American journal of human genetics. 2008 Feb

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• Review of 54 patients with complete DiGeorge anomaly enrolled in protocols for thymus transplantation: outcome of 44 consecutive transplants.

  The purpose of this study was to characterize a large group of infants with complete DiGeorge anomaly and to evaluate the ability of thymus transplant…

  Authors: M Louise Markert, Blythe H Devlin, Marilyn J Alexieff, Jie Li, Elizabeth A McCarthy, Stephanie E Gupton, Ivan K Chinn, Laura P Hale, Thomas B Kepler, Min He,…

  Source: Blood. 2007 May 15

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• Resection of hepatocellular adenoma in patients with glycogen storage disease type Ia.

  BACKGROUND/AIMS: Because dietary modifications have prolonged the life expectancy of patients with glycogen storage disease type Ia (GSD Ia), the inci…

  Authors: Srinevas K Reddy, Priya S Kishnani, Jennifer A Sullivan, Dwight D Koeberl, Dev M Desai, Michael A Skinner, Henry E Rice, Bryan M Clary

  Source: Journal of hepatology. 2007 Nov

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• Postnatal thymus transplantation with immunosuppression as treatment for DiGeorge syndrome.

  Complete DiGeorge syndrome is a fatal congenital disorder characterized by athymia, hypoparathyroidism, and heart defects. Less than half of patients …

  Authors: M Louise Markert, Marilyn J Alexieff, Jie Li, Marcella Sarzotti, Daniel A Ozaki, Blythe H Devlin, Debra A Sedlak, Gregory D Sempowski, Laura P Hale, Henry E Rice,…

  Source: Blood. 2004 Oct 15

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• RET activation inhibits doxorubicin-induced apoptosis in SK-N-MC cells.

  BACKGROUND: Medullary thyroid cancer (MTC) is generally resistant to chemotherapy and the frequent constitutive activation of RET (rearranged during t…

  Authors: Michael A Skinner, Karen E Lackey, Alex J Freemerman

  Source: Anticancer research. 2008 Jul-Aug

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• Surgical intervention in children with multiple endocrine neoplasia type 2.

  PURPOSE OF REVIEW: We provide a summary of the literature published in the past year addressing the surgical approach to multiple endocrine neoplasia …

  Authors: Melissa E Danko, Michael A Skinner

  Source: Current opinion in pediatrics. 2006 Jun

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• Clinical and hematologic benefits of partial splenectomy for congenital hemolytic anemias in children.

  OBJECTIVE: To assess the role of partial splenectomy for symptomatic children with various congenital hemolytic anemias. SUMMARY BACKGROUND DATA: The …

  Authors: Henry E Rice, Keith T Oldham, Cheryl A Hillery, Michael A Skinner, Sara M O'Hara, Russell E Ware

  Source: Annals of surgery. 2003 Feb

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• The discovery of substituted 4-(3-hydroxyanilino)-quinolines as potent RET kinase inhibitors.

  Substituted 4-(3-hydroxyanilino)-quinoline compounds, initially identified as small-molecule inhibitors of src family kinases, have been evaluated as …

  Authors: R Graham Robinett, Alex J Freemerman, Michael A Skinner, Lisa Shewchuk, Karen Lackey

  Source: Bioorganic & medicinal chemistry letters. 2007 Nov 1

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• Thymus transplantation in complete DiGeorge syndrome: immunologic and safety evaluations in 12 patients.

  Complete DiGeorge syndrome is a fatal condition in which infants have no detectable thymus function. The optimal treatment for the immune deficiency o…

  Authors: M Louise Markert, Marcella Sarzotti, Daniel A Ozaki, Gregory D Sempowski, Maria E Rhein, Laura P Hale, Francoise Le Deist, Marilyn J Alexieff, Jie Li, Elizabeth R Hauser,…

  Source: Blood. 2003 Aug 1

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• Postoperative outcomes of extremely low birth-weight infants with necrotizing enterocolitis or isolated intestinal perforation: a prospective cohort study by the NICHD Neonatal Research Network.

  OBJECTIVE: Purposes of this study were: 1) to compare mortality and postoperative morbidities (intra-abdominal abscess, wound dehiscence, and intestin…

  Authors: Martin L Blakely, Kevin P Lally, Scott McDonald, Rebeccah L Brown, Douglas C Barnhart, Richard R Ricketts, W Raleigh Thompson, L R Scherer, Michael D Klein, Robert W Letton,…

  Source: Annals of surgery. 2005 Jun

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