1 to 10 of 27 literature results

• Choreography of MAGUKs during T cell activation.

  T cell receptor activation requires the membrane-associated guanylate kinase CARMA1. A new study finds that a second such kinase, Dlgh1, is also requi…

  Authors: Mercedes Rincón, Roger J Davis

  Source: Nature immunology. 2007 Feb

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• Induction of hepatitis by JNK-mediated expression of TNF-alpha.

  The c-Jun NH(2)-terminal kinase (JNK) signaling pathway has been implicated in the development of tumor necrosis factor (TNF)-dependent hepatitis. JNK…

  Authors: Madhumita Das, Guadalupe Sabio, Feng Jiang, Mercedes Rincón, Richard A Flavell, Roger J Davis

  Source: Cell. 2009 Jan 23

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• Regulation of the immune response by stress-activated protein kinases.

  Activation of immune cells to mediate an immune response is often triggered by potential 'danger' or 'stress' stimuli that the organism receives. With…

  Authors: Mercedes Rincón, Roger J Davis

  Source: Immunological reviews. 2009 Mar

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• Methylation-controlled J protein promotes c-Jun degradation to prevent ABCB1 transporter expression.

  Methylation-controlled J protein (MCJ) is a newly identified member of the DnaJ family of cochaperones. Hypermethylation-mediated transcriptional sile…

  Authors: Ketki M Hatle, Wendy Neveu, Oliver Dienz, Stacia Rymarchyk, Ramiro Barrantes, Sarah Hale, Nicholas Farley, Karen M Lounsbury, Jeffrey P Bond, Douglas Taatjes,…

  Source: Molecular and cellular biology. 2007 Apr

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• p38 mitogen-activated protein kinase mediates the Fas-induced mitochondrial death pathway in CD8+ T cells.

  The p38 mitogen-activated protein kinase (MAPK) signaling pathway can be activated by a variety of stress stimuli such as UV radiation and osmotic str…

  Authors: Nicholas Farley, Gustavo Pedraza-Alva, Diego Serrano-Gomez, Viswas Nagaleekar, Alexander Aronshtam, Troy Krahl, Tina Thornton, Mercedes Rincón

  Source: Molecular and cellular biology. 2006 Mar

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• JNK and p38 MAP kinases in CD4+ and CD8+ T cells.

  The c-Jun aminoterminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase signaling pathways have been associated with cell death, different…

  Authors: Mercedes Rincón, Gustavo Pedraza-Alva

  Source: Immunological reviews. 2003 Apr

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• Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos.

  The extracellular signal-regulated kinases 1 and 2 (ERK1/2) are phosphorylated after inhalation of asbestos. The effect of blocking this signaling pat…

  Authors: Christopher B Manning, Tara Sabo-Attwood, Raymond F Robledo, Maximilian B Macpherson, Mercedes Rincón, Pamela Vacek, David Hemenway, Douglas J Taatjes, Patty J Lee, Brooke T Mossman

  Source: American journal of respiratory cell and molecular biology. 2008 May

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• Control of Borrelia burgdorferi-specific CD4+-T-cell effector function by interleukin-12- and T-cell receptor-induced p38 mitogen-activated protein kinase activity.

  Infection with Borrelia burgdorferi, the causative agent of Lyme disease, results in a Th1 response and proinflammatory cytokine production. Mice defi…

  Authors: Michael N Hedrick, Chris M Olson, Dietrich B Conze, Tonya C Bates, Mercedes Rincón, Juan Anguita

  Source: Infection and immunity. 2006 Oct

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• Salp15, an ixodes scapularis salivary protein, inhibits CD4(+) T cell activation.

  Tick saliva has pleiotropic properties that facilitate persistence of the arthropod upon the host. We now describe a feeding-inducible protein in Ixod…

  Authors: Juan Anguita, Nandhini Ramamoorthi, Joppe W R Hovius, Subrata Das, Venetta Thomas, Rafal Persinski, Dietrich Conze, Philip W Askenase, Mercedes Rincón, Fred S Kantor,…

  Source: Immunity. 2002 Jun

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• c-Jun N-terminal kinase 1 is required for Toll-like receptor 1 gene expression in macrophages.

  The regulation of innate immune responses to pathogens occurs through the interaction of Toll-like receptors (TLRs) with pathogen-associated molecular…

  Authors: Hooman Izadi, Amirreza T Motameni, Tonya C Bates, Elias R Olivera, Vega Villar-Suarez, Ila Joshi, Renu Garg, Barbara A Osborne, Roger J Davis, Mercedes Rincón,…

  Source: Infection and immunity. 2007 Oct

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