1 to 7 of 7 literature results

• Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.

  Multiple sclerosis is an inflammatory disease of the central nervous system that begins as a relapsing-remitting disease (RRMS) and is followed by a p…

  Authors: Mauricio F Farez, Francisco J Quintana, Roopali Gandhi, Guillermo Izquierdo, Miguel Lucas, Howard L Weiner

  Source: Nature immunology. 2009 Sep

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• Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.

  Regulatory T cells (T(reg)) expressing the transcription factor Foxp3 control the autoreactive components of the immune system. The development of T(r…

  Authors: Francisco J Quintana, Alexandre S Basso, Antonio H Iglesias, Thomas Korn, Mauricio F Farez, Estelle Bettelli, Mario Caccamo, Mohamed Oukka, Howard L Weiner

  Source: Nature. 2008 May 1

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• Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.

  Authors: Mauricio F Farez, Francisco J Quintana, Roopali Gandhi, Guillermo Izquierdo, Miguel Lucas, Howard L Weiner

  Source: Nature immunology. 2010 Jan

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• Systems biology approaches for the study of multiple sclerosis.

  Multiple sclerosis (MS) is a progressive neurological disease caused by an autoimmune attack to the central nervous system (CNS). MS is thought to res…

  Authors: Francisco J Quintana, Mauricio F Farez, Howard L Weiner

  Source: Journal of cellular and molecular medicine. 2008 Aug

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• Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells.

  INTRODUCTION: Parenteral OKT3 is used to treat transplant rejection and a humanized anti-CD3 Mab has shown positive clinical effects in new onset diab…

  Authors: Yaron Ilan, Ehud Zigmond, Gadi Lalazar, Adi Dembinsky, Ami Ben Ya'acov, Nila Hemed, Ibrahim Kasis, Elizabeth Axelrod, Lidya Zolotarov, Athalia Klein,…

  Source: Journal of clinical immunology. 2010 Jan

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• Adaptive autoimmunity and foxp3-based immunoregulation in zebrafish.

  BACKGROUND: Jawed vertebrates generate their immune-receptor repertoire by a recombinatorial mechanism that has the potential to produce harmful autor…

  Authors: Francisco J Quintana, Antonio H Iglesias, Mauricio F Farez, Mario Caccamo, Evan J Burns, Nasim Kassam, Mohamed Oukka, Howard L Weiner

  Source: PloS one. 2010

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• Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis.

  Multiple sclerosis (MS) is a chronic relapsing disease of the central nervous system (CNS) in which immune processes are believed to play a major role…

  Authors: Francisco J Quintana, Mauricio F Farez, Vissia Viglietta, Antonio H Iglesias, Yifat Merbl, Guillermo Izquierdo, Miguel Lucas, Alexandre S Basso, Samia J Khoury, Claudia F Lucchinetti,…

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2008 Dec 2

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