1 to 3 of 3 literature results

• High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation.

  The inability of myeloid chronic myelogenous leukemia blast crisis (CML-BC) progenitors to undergo neutrophil differentiation depends on suppression o…

  Authors: Ji Suk Chang, Ramasamy Santhanam, Rossana Trotta, Paolo Neviani, Anna M Eiring, Edward Briercheck, Mattia Ronchetti, Denis C Roy, Bruno Calabretta, Michael A Caligiuri,…

  Source: Blood. 2007 Aug 1

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• Design of an irreversible electroporation system for clinical use.

  Irreversible electroporation is an ablation modality in which microseconds, high-voltage electrical pulses are applied to induce cell necrosis in a ta…

  Authors: Claudio Bertacchini, Pier M Margotti, Enrico Bergamini, Andrea Lodi, Mattia Ronchetti, Ruggero Cadossi

  Source: Technology in cancer research & treatment. 2007 Aug

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• Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.

  Imatinib mesylate (IM), a potent inhibitor of the BCR/ABL tyrosine kinase, has become standard first-line therapy for patients with chronic myeloid le…

  Authors: Cristian Bellodi, Maria Rosa Lidonnici, Ashley Hamilton, G Vignir Helgason, Angela Rachele Soliera, Mattia Ronchetti, Sara Galavotti, Kenneth W Young, Tommaso Selmi, Rinat Yacobi,…

  Source: The Journal of clinical investigation. 2009 May

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