1 to 10 of 48 literature results

• Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis.

  RATIONALE: Structural alterations to airway smooth muscle (ASM) are a feature of asthma and cystic fibrosis (CF) in adults. OBJECTIVES: We investigate…

  Authors: Nicolas Regamey, Matthias Ochs, Tom N Hilliard, Christian Mühlfeld, Nikki Cornish, Louise Fleming, Sejal Saglani, Eric W F W Alton, Andrew Bush, Peter K Jeffery,…

  Source: American journal of respiratory and critical care medicine. 2008 Apr 15

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• Morphological alterations of exogenous surfactant inhibited by meconium can be prevented by dextran.

  BACKGROUND: Surfactant dysfunction due to inhibition is involved in the pathophysiology of meconium aspiration syndrome. Dextran addition has been sho…

  Authors: Matthias Ochs, Markus Schüttler, Guido Stichtenoth, Egbert Herting

  Source: Respiratory research. 2006

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• Reprint of "Stereology meets electron tomography: towards quantitative 3D electron microscopy" [J. Struct. Biol. 159 (2007) 443-450].

  Stereological tools are the gold standard for accurate (i.e., unbiased) and precise quantification of any microscopic sample. The past decades have pr…

  Authors: Dimitri Vanhecke, Daniel Studer, Matthias Ochs

  Source: Journal of structural biology. 2008 Mar

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• Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type II cells.

  BACKGROUND: Prophylactic exogenous surfactant therapy is a promising way to attenuate the ischemia and reperfusion (I/R) injury associated with lung t…

  Authors: Niels Dreyer, Christian Mühlfeld, Antonia Fehrenbach, Thomas Pech, Sebastian von Berg, Ragi Nagib, Joachim Richter, Thorsten Wittwer, Thorsten Wahlers, Matthias Ochs

  Source: Respiratory research. 2008

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• Alterations of alveolar type II cells and intraalveolar surfactant after bronchoalveolar lavage and perfluorocarbon ventilation. An electron microscopical and stereological study in the rat lung.

  BACKGROUND: Repeated bronchoalveolar lavage (BAL) has been used in animals to induce surfactant depletion and to study therapeutical interventions of …

  Authors: Mario Rüdiger, Sebastian Wendt, Lars Köthe, Wolfram Burkhardt, Roland R Wauer, Matthias Ochs

  Source: Respiratory research. 2007

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• Stereology meets electron tomography: towards quantitative 3D electron microscopy.

  Stereological tools are the gold standard for accurate (i.e., unbiased) and precise quantification of any microscopic sample. The past decades have pr…

  Authors: Dimitri Vanhecke, Daniel Studer, Matthias Ochs

  Source: Journal of structural biology. 2007 Sep

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• An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure.

  Authors: Connie C W Hsia, Dallas M Hyde, Matthias Ochs, Ewald R Weibel, ATS/ERS Joint Task Force on Quantitative Assessment of Lung Structure

  Source: American journal of respiratory and critical care medicine. 2010 Feb 15

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• Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice.

  BACKGROUND: Surfactant protein D (SP-D) deficient mice develop emphysema-like pathology associated with focal accumulations of foamy alveolar macropha…

  Authors: Lars Knudsen, Matthias Ochs, Rosemarie Mackay, Paul Townsend, Roona Deb, Christian Mühlfeld, Joachim Richter, Fabian Gilbert, Samuel Hawgood, Kenneth Reid,…

  Source: Respiratory research. 2007

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• Alteration of the pulmonary surfactant system in full-term infants with hereditary ABCA3 deficiency.

  RATIONALE: ABCA3 mutations are known to cause fatal surfactant deficiency. OBJECTIVE: We studied ABCA3 protein expression in full-term newborns with u…

  Authors: Frank Brasch, Sven Schimanski, Christian Mühlfeld, Stefan Barlage, Thomas Langmann, Charalampos Aslanidis, Alfred Boettcher, Ashraf Dada, Horst Schroten, Eva Mildenberger,…

  Source: American journal of respiratory and critical care medicine. 2006 Sep 1

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• The number of alveoli in the human lung.

  The number of alveoli is a key structural determinant of lung architecture. A design-based stereologic approach was used for the direct and unbiased e…

  Authors: Matthias Ochs, Jens R Nyengaard, Anja Jung, Lars Knudsen, Marion Voigt, Thorsten Wahlers, Joachim Richter, Hans Jørgen G Gundersen

  Source: American journal of respiratory and critical care medicine. 2004 Jan 1

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