1 to 9 of 9 literature results

• Tip60 in DNA damage response and growth control: many tricks in one HAT.

  The Tip60 histone acetyltransferase is part of an evolutionarily conserved multisubunit complex, NuA4, which is recruited by many transcription factor…

  Authors: Massimo Squatrito, Chiara Gorrini, Bruno Amati

  Source: Trends in cell biology. 2006 Sep

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• Radiation resistance and stem-like cells in brain tumors.

  The concepts of stem cells being resistant to therapy, stem-like cells existing in brain tumors, and these tumors initially responding to therapy foll…

  Authors: Dolores Hambardzumyan, Massimo Squatrito, Massimo Squartro, Eric C Holland

  Source: Cancer cell. 2006 Dec

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• Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas.

  The miR-17 approximately 92 cluster is frequently amplified or overexpressed in human cancers and has emerged as the prototypical oncogenic polycistro…

  Authors: Ping Mu, Yoon-Chi Han, Doron Betel, Evelyn Yao, Massimo Squatrito, Paul Ogrodowski, Elisa de Stanchina, Aleco D'Andrea, Chris Sander, Andrea Ventura

  Source: Genes & development. 2009 Dec 15

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• Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.

  The acetyl-transferase Tip60 might influence tumorigenesis in multiple ways. First, Tip60 is a co-regulator of transcription factors that either promo…

  Authors: Chiara Gorrini, Massimo Squatrito, Chiara Luise, Nelofer Syed, Daniele Perna, Landon Wark, Francesca Martinato, Domenico Sardella, Alessandro Verrecchia, Samantha Bennett,…

  Source: Nature. 2007 Aug 30

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• EBP1 is a nucleolar growth-regulating protein that is part of pre-ribosomal ribonucleoprotein complexes.

  EBP1 was identified as a protein that interacts with the ErbB-3 receptor and possibly contributes to transducing growth regulatory signals. The existe…

  Authors: Massimo Squatrito, Monica Mancino, Maddalena Donzelli, Liliana B Areces, Giulio F Draetta

  Source: Oncogene. 2004 May 27

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• Ebp1 is a dsRNA-binding protein associated with ribosomes that modulates eIF2alpha phosphorylation.

  dsRNA-binding domains (dsRBDs) characterize an expanding family of proteins involved in different cellular processes, ranging from RNA editing and pro…

  Authors: Massimo Squatrito, Monica Mancino, Leonardo Sala, Giulio F Draetta

  Source: Biochemical and biophysical research communications. 2006 Jun 9

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• Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.

  eNOS expression is elevated in human glioblastomas and correlated with increased tumor growth and aggressive character. We investigated the potential …

  Authors: Nikki Charles, Tatsuya Ozawa, Massimo Squatrito, Anne-Marie Bleau, Cameron W Brennan, Dolores Hambardzumyan, Eric C Holland

  Source: Cell stem cell. 2010 Feb 5

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• Glioma formation, cancer stem cells, and akt signaling.

  Several recent reports have provided evidence that cancer is initiated by a rare fraction of cells called "cancer stem cells" which are multipotent, s…

  Authors: Dolores Hambardzumyan, Massimo Squatrito, Eletha Carbajal, Eric C Holland

  Source: Stem cell reviews. 2008 Sep

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• Dual mode of degradation of Cdc25 A phosphatase.

  The Cdc25 dual-specificity phosphatases control progression through the eukaryotic cell division cycle by activating cyclin-dependent kinases. Cdc25 A…

  Authors: Maddalena Donzelli, Massimo Squatrito, Dvora Ganoth, Avram Hershko, Michele Pagano, Giulio F Draetta

  Source: The EMBO journal. 2002 Sep 16

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