1 to 6 of 6 literature results

• Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells.

  It is widely accepted that T helper type 1 (T(H)1) cytokines such as interferon-gamma (IFN-gamma) antagonize allergic diseases mediated by T(H)2 cytok…

  Authors: Martin E Dahl, Karim Dabbagh, Denny Liggitt, Sung Kim, David B Lewis

  Source: Nature immunology. 2004 Mar

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• Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice.

  The cytokine thymic stromal lymphopoietin (TSLP) has been linked to human allergic inflammatory diseases. We show here that TSLP expression was increa…

  Authors: Baohua Zhou, Michael R Comeau, Thibaut De Smedt, H Denny Liggitt, Martin E Dahl, David B Lewis, Dora Gyarmati, Theingi Aye, Daniel J Campbell, Steven F Ziegler

  Source: Nature immunology. 2005 Oct

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• Influenza A virus elevates active cathepsin B in primary murine DC.

  Dendritic cells (DCs) act as a first-line recognition system for invading pathogens, such as influenza A. The interaction of DC with influenza A virus…

  Authors: Timo Burster, Thierry Giffon, Martin E Dahl, Pia Björck, Matthew Bogyo, Ekkehard Weber, Kutubuddin Mahmood, David B Lewis, Elizabeth D Mellins

  Source: International immunology. 2007 May

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• A novel CCR5-specific pharmacodynamic assay in whole blood using phosphoflow cytometry highlights different ligand-dependent responses but similar properties of antagonists in CD8+ and CD4+ T lymphocytes.

  Chemokine CC motif receptor (CCR) 5 is a major drug target for both inflammation and virology indications. The primary function of CCR5 is to mediate …

  Authors: Martin E Dahl, Amy Berson, Jose Lora, Maria Fuentes

  Source: The Journal of pharmacology and experimental therapeutics. 2008 Dec

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• Chemotactic responses of IL-4-, IL-10-, and IFN-gamma-producing CD4+ T cells depend on tissue origin and microbial stimulus.

  Th1- and Th2-polarized immune responses are crucial in the defense against pathogens but can also promote autoimmunity and allergy. The chemokine rece…

  Authors: Gudrun F Debes, Martin E Dahl, Azita J Mahiny, Kerstin Bonhagen, Daniel J Campbell, Kerstin Siegmund, Klaus J Erb, David B Lewis, Thomas Kamradt, Alf Hamann

  Source: Journal of immunology (Baltimore, Md. : 1950). 2006 Jan 1

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• Toll-like receptor 4 is required for optimal development of Th2 immune responses: role of dendritic cells.

  LPS potently induces dendritic cell maturation and the production of proinflammatory cytokines, such as IL-12, by activation of Toll-like receptor 4 (…

  Authors: Karim Dabbagh, Martin E Dahl, Pamela Stepick-Biek, David B Lewis

  Source: Journal of immunology (Baltimore, Md. : 1950). 2002 May 1

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