1 to 10 of 23 literature results

• Foxp3+ regulatory T cells: differentiation, specification, subphenotypes.

  Regulatory T cells (T(reg) cells) characterized by expression of the transcription factor Foxp3 play a key role in immune homeostasis. Rather than a m…

  Authors: Markus Feuerer, Jonathan A Hill, Diane Mathis, Christophe Benoist

  Source: Nature immunology. 2009 Jul

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• Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.

  Obesity is accompanied by chronic, low-grade inflammation of adipose tissue, which promotes insulin resistance and type-2 diabetes. These findings rai…

  Authors: Markus Feuerer, Laura Herrero, Daniela Cipolletta, Afia Naaz, Jamie Wong, Ali Nayer, Jongsoon Lee, Allison B Goldfine, Christophe Benoist, Steven Shoelson,…

  Source: Nature medicine. 2009 Aug

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• How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets.

  CD4(+)Foxp3(+) regulatory T cells (Treg cells) are known to control the progression of autoimmune diabetes, but when, where, and how they exert their …

  Authors: Markus Feuerer, Yuelei Shen, Dan R Littman, Christophe Benoist, Diane Mathis

  Source: Immunity. 2009 Oct 16

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• Green T(R) cells.

  Identification of the transcription factor Foxp3 as a "master regulator" of regulatory T (T(R)) cells was a major discovery. A new study by Fontenot e…

  Authors: Markus Feuerer, Christophe Benoist, Diane Mathis

  Source: Immunity. 2005 Mar

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• Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature.

  The CD4(+)CD25(+) lineage of regulatory T (Treg) cells plays a key role in controlling immune and autoimmune responses and is characterized by a uniqu…

  Authors: Jonathan A Hill, Markus Feuerer, Kaley Tash, Sokol Haxhinasto, Jasmine Perez, Rachel Melamed, Diane Mathis, Christophe Benoist

  Source: Immunity. 2007 Nov

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• FOXP3 controls regulatory T cell function through cooperation with NFAT.

  Antigen stimulation of immune cells activates the transcription factor NFAT, a key regulator of T cell activation and anergy. NFAT forms cooperative c…

  Authors: Yongqing Wu, Madhuri Borde, Vigo Heissmeyer, Markus Feuerer, Ariya D Lapan, James C Stroud, Darren L Bates, Liang Guo, Aidong Han, Steven F Ziegler,…

  Source: Cell. 2006 Jul 28

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• Bone marrow as a priming site for T-cell responses to blood-borne antigen.

  Although bone marrow is known as a primary lymphoid organ, its potential to serve as a secondary immune organ has hardly been explored. Here we demons…

  Authors: Markus Feuerer, Philipp Beckhove, Natalio Garbi, Yolanda Mahnke, Andreas Limmer, Mirja Hommel, Günter J Hämmerling, Bruno Kyewski, Alf Hamann, Viktor Umansky,…

  Source: Nature medicine. 2003 Sep

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• Enrichment of functional CD8 memory T cells specific for MUC1 in bone marrow of patients with multiple myeloma.

  Multiple myeloma (MM) is one of the most common hematologic malignancies. Despite extensive therapeutical approaches, cures remain rare exceptions. An…

  Authors: Carmen Choi, Mathias Witzens, Marianna Bucur, Markus Feuerer, Nora Sommerfeldt, Andreas Trojan, Anthony Ho, Volker Schirrmacher, Hartmut Goldschmidt, Philipp Beckhove

  Source: Blood. 2005 Mar 1

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• Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo.

  Regulatory T cells (Tregs) play a fundamental role in the suppression of different immune responses; however, compartments at which they exert suppres…

  Authors: Kerstin Siegmund, Markus Feuerer, Christiane Siewert, Saeed Ghani, Uta Haubold, Anja Dankof, Veit Krenn, Michael P Schön, Alexander Scheffold, John B Lowe,…

  Source: Blood. 2005 Nov 1

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• T cells as pioneers: antigen-specific T cells condition inflamed sites for high-rate antigen-non-specific effector cell recruitment.

  Cellular infiltration is a classic hallmark of inflammation. Whereas the role of T cells in many types of inflammation is well established, the specif…

  Authors: Saeed Ghani, Markus Feuerer, Cornelia Doebis, Uta Lauer, Christoph Loddenkemper, Jochen Huehn, Alf Hamann, Uta Syrbe

  Source: Immunology. 2009 Sep

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