1 to 4 of 4 literature results

• Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44.

  Hyaluronic acid (HA) promotes tumor metastasis and is an accurate diagnostic marker for bladder cancer. HA is synthesized by HA synthases HAS1, HAS2, …

  Authors: Roozbeh Golshani, Luis Lopez, Veronica Estrella, Mario Kramer, Naoko Iida, Vinata B Lokeshwar

  Source: Cancer research. 2008 Jan 15

  View Full Text

• HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer.

  Tumor cells express HYAL1 hyaluronidase, which degrades hyaluronic acid. HYAL1 expression in bladder cancer cells promotes tumor growth, invasion, and…

  Authors: Vinata B Lokeshwar, Veronica Estrella, Luis Lopez, Mario Kramer, Pablo Gomez, Mark S Soloway, Bal L Lokeshwar

  Source: Cancer research. 2006 Dec 1

  View Full Text

• PTEN and p27Kip1 are not downregulated in the majority of renal cell carcinomas--implications for Akt activation.

  Activation of the PKB/Akt pathway is supposed to substantially contribute to the pathogenesis and progression of malignant disease. The present study …

  Authors: Joerg Hennenlotter, Petra A Ohneseit, Perikles Simon, Axel S Merseburger, Juergen Serth, Ursula Kuehs, Mario Kramer, Joerg T Hartmann, Arnulf Stenzl, Markus A Kuczyk

  Source: Oncology reports. 2008 May

  View Full Text

• Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter.

  HYAL-1 (hyaluronoglucosaminidase-1) belongs to the hyaluronidase family of enzymes that degrade hyaluronic acid. HYAL-1 is a marker for cancer diagnos…

  Authors: Vinata B Lokeshwar, Pablo Gomez, Mario Kramer, Judith Knapp, Melissa A McCornack, Luis E Lopez, Nevis Fregien, Neetika Dhir, Steve Scherer, David J Klumpp,…

  Source: The Journal of biological chemistry. 2008 Oct 24

  View Free Full Text