1 to 9 of 9 literature results

• Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene.

  Autism is a genetically complex neurodevelopmental syndrome in which language deficits are a core feature. We describe results from two complimentary …

  Authors: Maricela Alarcón, Brett S Abrahams, Jennifer L Stone, Jacqueline A Duvall, Julia V Perederiy, Jamee M Bomar, Jonathan Sebat, Michael Wigler, Christa L Martin, David H Ledbetter,…

  Source: American journal of human genetics. 2008 Jan

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• Replication of autism linkage: fine-mapping peak at 17q21.

  Autism is a heritable but genetically complex disorder characterized by deficits in language and in reciprocal social interactions, combined with repe…

  Authors: Rita M Cantor, Naoko Kono, Jackie A Duvall, Ana Alvarez-Retuerto, Jennifer L Stone, Maricela Alarcón, Stanley F Nelson, Daniel H Geschwind

  Source: American journal of human genetics. 2005 Jun

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• Search for autism loci by combined analysis of Autism Genetic Resource Exchange and Finnish families.

  OBJECTIVE: Several genome-wide screens have been performed in autism spectrum disorders resulting in the identification of numerous putative susceptib…

  Authors: Tero Ylisaukko-oja, Maricela Alarcón, Rita M Cantor, Mari Auranen, Raija Vanhala, Elli Kempas, Lennart von Wendt, Irma Järvelä, Daniel H Geschwind, Leena Peltonen

  Source: Annals of neurology. 2006 Jan

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• A genomewide screen of 345 families for autism-susceptibility loci.

  We previously reported a genomewide scan to identify autism-susceptibility loci in 110 multiplex families, showing suggestive evidence (P <.01) for li…

  Authors: Amanda L Yonan, Maricela Alarcón, Rong Cheng, Patrik K E Magnusson, Sarah J Spence, Abraham A Palmer, Adina Grunn, Suh-Hang Hank Juo, Joseph D Terwilliger, Jianjun Liu,…

  Source: American journal of human genetics. 2003 Oct

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• Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families.

  Autism is a syndrome characterized by deficits in language and social skills and by repetitive behaviors. We hypothesized that potential quantitative …

  Authors: Maricela Alarcón, Rita M Cantor, Jianjun Liu, T Conrad Gilliam, Daniel H Geschwind, Autism Genetic Research Exchange Consortium

  Source: American journal of human genetics. 2002 Jan

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• Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease.

  BACKGROUND: Serotonin has been linked to neuropsychiatric symptoms in Alzheimer disease, mainly agitation/aggression, depression, and psychosis. Neuro…

  Authors: Frédéric Assal, Maricela Alarcón, Esther C Solomon, Donna Masterman, Daniel H Geschwind, Jeffrey L Cummings

  Source: Archives of neurology. 2004 Aug

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• A functional genetic link between distinct developmental language disorders.

  BACKGROUND: Rare mutations affecting the FOXP2 transcription factor cause a monogenic speech and language disorder. We hypothesized that neural pathwa…

  Authors: Sonja C Vernes, Dianne F Newbury, Brett S Abrahams, Laura Winchester, Jérôme Nicod, Matthias Groszer, Maricela Alarcón, Peter L Oliver, Kay E Davies, Daniel H Geschwind,…

  Source: The New England journal of medicine. 2008 Nov 27

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• Stratification based on language-related endophenotypes in autism: attempt to replicate reported linkage.

  The identification of autism susceptibility genes has been hampered by phenotypic heterogeneity of autism, among other factors. However, the use of en…

  Authors: Sarah J Spence, Rita M Cantor, Lien Chung, Sharon Kim, Daniel H Geschwind, Maricela Alarcón

  Source: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2006 Sep 5

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• Association between human mu-opioid receptor gene polymorphism, pain tolerance, and opioid addiction.

  Central to both pain responses and opioid addiction is activity at the micro -opioid receptor. To explore the role of the micro -opioid receptor gene …

  Authors: Peggy Compton, Daniel H Geschwind, Maricela Alarcón

  Source: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2003 Aug 15

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