1 to 10 of 21 literature results

• RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia.

  SUMO conjugation to proteins is involved in the regulation of diverse cellular functions. We have identified a protein, RWD-containing sumoylation enh…

  Authors: Alberto Carbia-Nagashima, Juan Gerez, Carolina Perez-Castro, Marcelo Paez-Pereda, Susana Silberstein, Günter K Stalla, Florian Holsboer, Eduardo Arzt

  Source: Cell. 2007 Oct 19

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• The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells.

  Rapamycin and its analogues have significant antiproliferative action against a variety of tumors. However, sensitivity to rapamycin is reduced by Akt…

  Authors: Vesna Cerovac, Jose Monteserin-Garcia, Hadara Rubinfeld, Michael Buchfelder, Marco Losa, Tullio Florio, Marcelo Paez-Pereda, Günter K Stalla, Marily Theodoropoulou

  Source: Cancer research. 2010 Jan 15

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• Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression.

  Somatostatin limits cell growth by inhibiting the proliferative activity of growth factor receptors. In this study, it is shown that in pituitary tumo…

  Authors: Marily Theodoropoulou, Jing Zhang, Sandra Laupheimer, Marcelo Paez-Pereda, Christophe Erneux, Tullio Florio, Uberto Pagotto, Günter K Stalla

  Source: Cancer research. 2006 Feb 1

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• P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder.

  The P2RX7 gene is located within a region on chromosome 12q24.31 that has been identified as a susceptibility locus for affective disorders by linkage…

  Authors: Susanne Lucae, Daria Salyakina, Nicholas Barden, Mario Harvey, Bernard Gagné, Michel Labbé, Elisabeth B Binder, Manfred Uhr, Marcelo Paez-Pereda, Inge Sillaber,…

  Source: Human molecular genetics. 2006 Aug 15

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• Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine.

  INTRODUCTION: Monoamine-based antidepressants inhibit neurotransmitter reuptake within short time. However, it commonly takes several weeks until clin…

  Authors: Inge Sillaber, Markus Panhuysen, Markus S H Henniger, Frauke Ohl, Claudia Kühne, Benno Pütz, Thomas Pohl, Jan M Deussing, Marcelo Paez-Pereda, Florian Holsboer

  Source: Psychopharmacology. 2008 Nov

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• Modulation of growth hormone and prolactin secretion in Trypanosoma cruzi-infected mammosomatotrophic cells.

  OBJECTIVE: In a previous study, we reported an imbalance in the hypothalamus-pituitary-adrenal axis of mice acutely infected with the protozoan parasi…

  Authors: Eliane Corrêa-de-Santana, Marcelo Paez-Pereda, Marily Theodoropoulou, Ulrich Renner, Johanna Stalla, Günter Karl Stalla, Wilson Savino

  Source: Neuroimmunomodulation. 2009

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• Nur77 induction and activation are necessary for interleukin-1 stimulation of proopiomelanocortin in AtT-20 corticotrophs.

  Nur77 and Nurr1 are critical for proopiomelanocortin (POMC) regulation by corticotrophin releasing hormone (CRH) in corticotrophs. We analyze the regu…

  Authors: Damian Kovalovsky, Marcelo Paez Pereda, Marta Labeur, Ulrich Renner, Florian Holsboer, Günter K Stalla, Eduardo Arzt

  Source: FEBS letters. 2004 Apr 9

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• Hypothalamus-pituitary-adrenal axis during Trypanosoma cruzi acute infection in mice.

  Functional interactions between neuroendocrine and immune systems are mediated by similar ligands and receptors, which establish a bi-directional comm…

  Authors: Eliane Corrêa-de-Santana, Marcelo Paez-Pereda, Marily Theodoropoulou, Oscar Kenji Nihei, Yvonne Gruebler, Marcelo Bozza, Eduardo Arzt, Déa Maria Serra Villa-Verde, Ulrich Renner, Johanna Stalla,…

  Source: Journal of neuroimmunology. 2006 Apr

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• Intrapituitary expression and regulation of the gp130 cytokine interleukin-6 and its implication in pituitary physiology and pathophysiology.

  Interleukin (IL)-6, a member of the gp130 cytokine family, is sometimes designated as an "endocrine" cytokine because of its strong regulatory influen…

  Authors: Ulrich Renner, Eliane Correa De Santana, Juan Gerez, Bianca Fröhlich, Mariana Haedo, Marcelo Paez Pereda, Chiara Onofri, Günter K Stalla, Eduardo Arzt

  Source: Annals of the New York Academy of Sciences. 2009 Feb

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• Potential of retinoic acid derivatives for the treatment of corticotroph pituitary adenomas.

  Cushing's disease is a severe clinical condition caused by hypersecretion of corticosteroids due to excessive ACTH secretion from a pituitary adenoma.…

  Authors: Marta Labeur, Marcelo Paez-Pereda, Eduardo Arzt, Günter K Stalla

  Source: Reviews in endocrine & metabolic disorders. 2009 Jun

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