1 to 6 of 6 literature results

• Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels.

  The survival of T lymphocytes requires sustained, Ca(2+) influx-dependent gene expression. The molecular mechanism that governs sustained Ca(2+) influ…

  Authors: Mithilesh K Jha, Abdallah Badou, Marcel Meissner, John E McRory, Marc Freichel, Veit Flockerzi, Richard A Flavell

  Source: Nature immunology. 2009 Dec

  View Full Text

• Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4.

  Mast cells are key effector cells in allergic reactions. Aggregation of the receptor FcepsilonRI in mast cells triggers the influx of calcium (Ca(2+))…

  Authors: Rudi Vennekens, Jenny Olausson, Marcel Meissner, Wilhelm Bloch, Ilka Mathar, Stephan E Philipp, Frank Schmitz, Petra Weissgerber, Bernd Nilius, Veit Flockerzi,…

  Source: Nature immunology. 2007 Mar

  View Full Text

• Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in mice.

  AIMS: Cardiac L-type Ca(2+)-currents show distinct alterations in chronic heart failure, including increased single-channel activity and blunted adren…

  Authors: Nadine Beetz, Lutz Hein, Janos Meszaros, Ralf Gilsbach, Frederico Barreto, Marcel Meissner, Uta C Hoppe, Arnold Schwartz, Stefan Herzig, Jan Matthes

  Source: Cardiovascular research. 2009 Dec 1

  View Full Text

• Ca2+ channel currents and contraction in CaVbeta3-deficient ileum smooth muscle from mouse.

  Voltage activated L-type Ca(2+) channels are the principal Ca(2+) channels in intestinal smooth muscle cells. They comprise the ion conducting Ca(V)1 …

  Authors: Brigitte Held, Volodymyr Tsvilovskyy, Marcel Meissner, Lars Kaestner, Andreas Ludwig, Sven Mossmang, Peter Lipp, Marc Freichel, Veit Flockerzi

  Source: Cell calcium. 2007 Oct-Nov

  View Full Text

• Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.

  By now, little is known on L-type calcium channel (LTCC) subunits expressed in mouse heart. We show that CaVbeta2 proteins are the major CaVbeta compo…

  Authors: Sabine Link, Marcel Meissner, Brigitte Held, Andreas Beck, Petra Weissgerber, Marc Freichel, Veit Flockerzi

  Source: The Journal of biological chemistry. 2009 Oct 30

  View Full Text

• Specific detection and semi-quantitative analysis of TRPC4 protein expression by antibodies.

  In mouse tissues two variants of the transient receptor potential (canonical) (TRPC) 4 protein are expressed: the "full-length" TRPC4 protein and a sl…

  Authors: Veit Flockerzi, Christine Jung, Thomas Aberle, Marcel Meissner, Marc Freichel, Stephan E Philipp, Wolfgang Nastainczyk, Patrick Maurer, Richard Zimmermann

  Source: Pflügers Archiv : European journal of physiology. 2005 Oct

  View Full Text