1 to 10 of 11 literature results

• Proof-by-synthesis of the transcriptional logic of mammalian circadian clocks.

  Mammalian circadian clocks consist of complex regulatory loops mediated through--at least--morning, daytime and night-time DNA elements. To prove the …

  Authors: Maki Ukai-Tadenuma, Takeya Kasukawa, Hiroki R Ueda

  Source: Nature cell biology. 2008 Oct

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• A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock.

  The Drosophila circadian clock consists of integrated autoregulatory feedback loops, making the clock difficult to elucidate without comprehensively i…

  Authors: Akira Matsumoto, Maki Ukai-Tadenuma, Rikuhiro G Yamada, Jerry Houl, Kenichiro D Uno, Takeya Kasukawa, Brigitte Dauwalder, Taichi Q Itoh, Kuniaki Takahashi, Ryu Ueda,…

  Source: Genes & development. 2007 Jul 1

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• Detection of a circadian enhancer in the mDbp promoter using prokaryotic transposon vector-based strategy.

  In mammals, the expression of 5-10% of genes occurs with circadian fluctuation in various organs and tissues. This cyclic transcription is thought to …

  Authors: Yota B Kiyohara, Keigo Nishii, Maki Ukai-Tadenuma, Hiroki R Ueda, Yasuo Uchiyama, Kazuhiro Yagita

  Source: Nucleic acids research. 2008 Mar

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• CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA.

  Chromatin remodeling of type 2 cytokine gene loci occurs during differentiation of naive CD4 and CD8 T cells into type 2 helper (Th2) and cytotoxic (T…

  Authors: Miyuki Omori, Masakatsu Yamashita, Masamichi Inami, Maki Ukai-Tadenuma, Motoko Kimura, Yukiko Nigo, Hiroyuki Hosokawa, Akihiro Hasegawa, Masaru Taniguchi, Toshinori Nakayama

  Source: Immunity. 2003 Aug

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• Formation of an active form of the interleukin-2/15 receptor beta-chain by insertion of the intracisternal A particle in a radiation-induced mouse thymic lymphoma and its role in tumorigenesis.

  Although many reports suggest that aberrant regulation of cytokine signaling pathways via the interleukin-2 receptor (IL-2R) induces tumorigenic trans…

  Authors: Hideki Ukai, Hiroko Ishii-Oba, Maki Ukai-Tadenuma, Toshiaki Ogiu, Hideo Tsuji

  Source: Molecular carcinogenesis. 2003 Jun

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• A new technique to prevent self-ligation of DNA.

  The most widely used technique for preventing self-ligation (self-circularization and concatenation) of DNA is dephosphorylation of the 5'-end, which …

  Authors: Hideki Ukai, Maki Ukai-Tadenuma, Toshiaki Ogiu, Hideo Tsuji

  Source: Journal of biotechnology. 2002 Aug 28

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• Analysis and synthesis of high-amplitude Cis-elements in the mammalian circadian clock.

  Mammalian circadian clocks consist of regulatory loops mediated by Clock/Bmal1-binding elements, DBP/E4BP4 binding elements, and RevErbA/ROR binding e…

  Authors: Yuichi Kumaki, Maki Ukai-Tadenuma, Ken-ichiro D Uno, Junko Nishio, Koh-hei Masumoto, Mamoru Nagano, Takashi Komori, Yasufumi Shigeyoshi, John B Hogenesch, Hiroki R Ueda

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2008 Sep 30

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• Physical simulation of the transcriptional network of mammalian circadian clocks

  Authors: Maki Ukai-Tadenuma, Takeya Kasukawa, Hiroki R Ueda

  Source: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2009 Dec

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• CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.

  A striking feature of the circadian clock is its flexible yet robust response to various environmental conditions. To analyze the biochemical processe…

  Authors: Yasushi Isojima, Masato Nakajima, Hideki Ukai, Hiroshi Fujishima, Rikuhiro G Yamada, Koh-hei Masumoto, Reiko Kiuchi, Mayumi Ishida, Maki Ukai-Tadenuma, Yoichi Minami,…

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2009 Sep 15

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• Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci.

  GATA3 expression is essential for type-2 helper T (Th2) cell differentiation. GATA3-mediated chromatin remodeling at the Th2 cytokine gene loci, inclu…

  Authors: Masakatsu Yamashita, Maki Ukai-Tadenuma, Takeshi Miyamoto, Kaoru Sugaya, Hiroyuki Hosokawa, Akihiro Hasegawa, Motoko Kimura, Masaru Taniguchi, James DeGregori, Toshinori Nakayama

  Source: The Journal of biological chemistry. 2004 Jun 25

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