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Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Stu…
Authors: Masato Furuhashi, Gürol Tuncman, Cem Z Görgün, Liza Makowski, Genichi Atsumi, Eric Vaillancourt, Keita Kono, Vladimir R Babaev, Sergio Fazio, MacRae F Linton,…
Source: Nature. 2007 Jun 21
View Full TextAuthors: Sergio Fazio, MacRae F Linton
Source: Lancet. 2009 May 23
View Full TextMacrophage low-density lipoprotein receptor-related protein (LRP) mediates internalization of remnant lipoproteins, and it is generally thought that b…
Authors: Cheryl D Overton, Patricia G Yancey, Amy S Major, MacRae F Linton, Sergio Fazio
Source: Circulation research. 2007 Mar 16
View Full TextLow-density lipoprotein receptor-related protein (LRP-1) functions in endocytosis and in cell signaling directly (by binding signaling adaptor protein…
Authors: Alban Gaultier, Sanja Arandjelovic, Sherry Niessen, Cheryl D Overton, MacRae F Linton, Sergio Fazio, W Marie Campana, Benjamin F Cravatt, Steven L Gonias
Source: Blood. 2008 Jun 1
View Free Full TextBACKGROUND: The peroxisome proliferator-activated receptor-alpha (PPARalpha) plays important roles in lipid metabolism, inflammation, and atherosclero…
Authors: Vladimir R Babaev, Hiroyuki Ishiguro, Lei Ding, Patricia G Yancey, Dwayne E Dove, William J Kovacs, Clay F Semenkovich, Sergio Fazio, MacRae F Linton
Source: Circulation. 2007 Sep 18
View Full TextDirect binding of apolipoprotein (apo)B-containing lipoproteins to proteoglycans is the initiating event in atherosclerosis, but the processes involve…
Authors: Maria Gustafsson, Malin Levin, Kristina Skålén, Jeanna Perman, Vincent Fridén, Pernilla Jirholt, Sven-Olof Olofsson, Sergio Fazio, MacRae F Linton, Clay F Semenkovich,…
Source: Circulation research. 2007 Oct 12
View Full TextBACKGROUND: Cyclooxygenase-1 (COX-1) has been implicated in the pathogenesis of atherothrombosis and is expressed by the major cell types of atheroscl…
Authors: Vladimir R Babaev, Lei Ding, Jeff Reese, Jason D Morrow, Matthew D Breyer, Sudhansu K Dey, Sergio Fazio, MacRae F Linton
Source: Circulation. 2006 Jan 3
View Full TextBACKGROUND: Macrophage acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) and apolipoprotein E (apoE) have been implicated in regulating cellular c…
Authors: Yan Ru Su, Dwayne E Dove, Amy S Major, Alyssa H Hasty, Branden Boone, MacRae F Linton, Sergio Fazio
Source: Circulation. 2005 May 10
View Full TextBACKGROUND: The adipocyte fatty acid-binding protein (FABP) aP2 is expressed by adipocytes and macrophages and modulates insulin resistance, glucose a…
Authors: Jeffrey B Boord, Kazuhisa Maeda, Liza Makowski, Vladimir R Babaev, Sergio Fazio, MacRae F Linton, Gökhan S Hotamisligil
Source: Circulation. 2004 Sep 14
View Full TextGenetic studies have demonstrated an important role for proprotein convertase subtilisin/kexin type 9 (PCSK9) as a determinant of plasma cholesterol l…
Authors: Daping Fan, Patricia G Yancey, Shenfeng Qiu, Lei Ding, Edwin J Weeber, MacRae F Linton, Sergio Fazio
Source: Biochemistry. 2008 Feb 12
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