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Integrin activation is essential for the function of all blood cells, including platelets and leukocytes. The blood cell-specific FERM domain protein …
Authors: Markus Moser, Martina Bauer, Stephan Schmid, Raphael Ruppert, Sarah Schmidt, Michael Sixt, Hao-Ven Wang, Markus Sperandio, Reinhard Fässler
Source: Nature medicine. 2009 Mar
View Full TextLeukocyte recruitment encompasses cell adhesion and activation steps that enable circulating leukocytes to roll, arrest, and firmly adhere on the endo…
Authors: Markus Sperandio, Christian A Gleissner, Klaus Ley
Source: Immunological reviews. 2009 Jul
View Full TextThe mammalian actin-binding protein 1 (mAbp1, Hip-55, SH3P7) is phosphorylated by the nonreceptor tyrosine kinase Syk that has a fundamental effect fo…
Authors: Jürgen Schymeinsky, Ronald Gerstl, Ingrid Mannigel, Katy Niedung, David Frommhold, Klaus Panthel, Jürgen Heesemann, Michael Sixt, Thomas Quast, Waldemar Kolanus,…
Source: Blood. 2009 Nov 5
View Full TextThe CXC ligand (CXCL)12/CXC receptor (CXCR)4 chemokine-receptor axis controls hematopoiesis, organ development, and angiogenesis, but its role in the …
Authors: Alma Zernecke, Ilze Bot, Yassin Djalali-Talab, Erdenechimeg Shagdarsuren, Kiril Bidzhekov, Svenja Meiler, Regina Krohn, Andreas Schober, Markus Sperandio, Oliver Soehnlein,…
Source: Circulation research. 2008 Feb 1
View Full TextLeukocyte adhesion via beta(2) integrins (CD11/CD18) activates the tyrosine kinase Syk. We found that Syk was enriched at the lamellipodium during N-f…
Authors: Jurgen Schymeinsky, Anca Sindrilaru, David Frommhold, Markus Sperandio, Ronald Gerstl, Cornelia Then, Attila Mócsai, Karin Scharffetter-Kochanek, Barbara Walzog
Source: Blood. 2006 Dec 1
View Full TextBACKGROUND: Pancreatic infiltration by leucocytes represents a hallmark in acute pancreatitis. Although leucocytes play an active role in the pathophy…
Authors: E Ryschich, V Kerkadze, O Deduchovas, O Salnikova, A Parseliunas, A Märten, W Hartwig, M Sperandio, J Schmidt
Source: Gut. 2009 Nov
View Full TextLeukocyte adhesion deficiency II (LAD II), also known as congenital disorder of glycosylation IIc (CDG-IIc), is a human disease in which a defective G…
Authors: Sviatlana Yakubenia, David Frommhold, Dirk Schölch, Christina C Hellbusch, Christian Körner, Björn Petri, Claire Jones, Ute Ipe, M Gabriele Bixel, Robert Krempien,…
Source: Blood. 2008 Aug 15
View Full TextThe aim of this work was to evaluate and quantify the influence of denitrification of nitrate on the aerobic granular sludge development. Two parallel…
Authors: Junfeng Wan, Mathieu Sperandio
Source: Chemosphere. 2009 Apr
View Full TextBACKGROUND: Computed tomography has been shown to be useful in the evaluation of aortocoronary bypass grafts (CABG). This is the first prospective stu…
Authors: E Martuscelli, A Romagnoli, A D'Eliseo, M Tomassini, C Razzini, M Sperandio, G Simonetti, F Romeo, J L Mehta
Source: Circulation. 2004 Nov 16
View Full TextThe study regards para-nitrophenol (p-NP) removal by a mixed culture in a batch reactor under aerobic conditions performed at low ratio substrate (p-N…
Authors: Fériel Rezouga, Moktar Hamdi, Mathieu Sperandio
Source: Bioresource technology. 2009 Nov
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