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Early impairment of hepatitis C virus specific T cell proliferation during acute infection leads to failure of viral clearance.
BACKGROUND AND AIMS: Cellular mediated immunity (CMI) is thought to play a key role in resolution of primary hepatitis C virus (HCV) infection. Howeve…
Authors: A Folgori, E Spada, M Pezzanera, L Ruggeri, A Mele, A R Garbuglia, M P Perrone, P Del Porto, E Piccolella, R Cortese,…
Source: Gut. 2006 Jul
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Multispecific T cell response and negative HCV RNA tests during acute HCV infection are early prognostic factors of spontaneous clearance.
BACKGROUND/AIMS: Hepatitis C virus (HCV) infection results in a high frequency of chronic disease. The aim of this study was to identify early prognos…
Authors: E Spada, A Mele, A Berton, L Ruggeri, L Ferrigno, A R Garbuglia, M P Perrone, G Girelli, P Del Porto, E Piccolella,…
Source: Gut. 2004 Nov
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T cell response to N-formylated peptides in humans.
We present the first evidence of a T lymphocyte response to N-formylated peptides in humans. N-formylated peptide sequences from self (mitochondrial) …
Authors: G Ristori, C Montesperelli, M T Fiorillo, L Battistini, A Chersi, R Sorrentino, G Borsellino, A Perna, D Tramonti, S Cannoni,…
Source: European journal of immunology. 2001 Sep
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Pre-transplant prognostic factors for patients with high-risk leukemia undergoing an unrelated cord blood transplantation.
From July 1995 to December 2001, 42 patients with leukemia aged 1-42 years underwent cord blood transplant (CBT) from unrelated, < or = 2 antigen HLA …
Authors: A P Iori, R Cerretti, L De Felice, M Screnci, A Mengarelli, A Romano, M Caniglia, L Cerilli, G Gentile, M L Moleti,…
Source: Bone marrow transplantation. 2004 Jun
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HLA-C and HLA-DQB1 compatibility in unrelated cord blood transplants.
BACKGROUND AND OBJECTIVE: Umbilical cord blood (UCB) cells have been definitively proved to be a source of hematopoietic stem cells with repopulating …
Authors: L Elia, W Arcese, M Torello, A P Iori, C Guglielmi, M P Perrone, M Screnci, T Sprovieri, M C Rapanotti, G Cimino
Source: Haematologica. 1999 Jun
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Pathophysiology of heart failure.
Heart failure is a leading cause of mortality and morbidity in Western countries. Common etiology is mostly represented by ischemic and hypertensive h…
Authors: M Chiariello, P Perrone-Filardi
Source: Mineral and electrolyte metabolism. 1999 Jan-Apr
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Growth modulation of freshly isolated non-Hodgkin's B-lymphoma cells induced by various cytokines and all-trans-retinoic-acid.
We investigated the potential of ten cytokines (IL2, IL3, IL4, IL6, IL10, IL13, G-CSF, GM-CSF, interferon alpha, interferon gamma) and all-trans-retin…
Authors: T Bonnefoix, R Gressin, M Jacrot, P Perron, P Swiercz, P Chaffanjon, J J Sotto
Source: Leukemia & lymphoma. 1997 Mar
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Idarubicin intensified BUCY2 regimen in allogeneic unmanipulated transplant for high-risk hematological malignancies.
Twenty-nine consecutive patients with high-risk hematological malignancy aged from 3 to 58 years underwent an unmanipulated graft from an HLA-identica…
Authors: A Mengarelli, A P Iori, C Guglielmi, M P Perrone, M Gozzer, C Girmenia, G Cimino, A M Testi, R Ricci, L De Felice,…
Source: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2000 Dec
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Reduction in infarct size by the phospholipase inhibitor quinacrine in dogs with coronary artery occlusion.
It has been suggested that activation of tissue phospholipases may contribute to the development of ischemic cell injury. In the present study we soug…
Authors: M Chiariello, G Ambrosio, M Cappelli-Bigazzi, P Perrone-Filardi, I Tritto, E Nevola, P Golino
Source: American heart journal. 1990 Oct
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A second example of hemolysis due to IgA autoantibody with anti-e specificity.
A case of warm autoimmune hemolytic anemia due to IgA antibody is described. The patient had clinical and hematologic signs of hyperhemolysis, but all…
Authors: G Girelli, M P Perrone, G Adorno, M C Arista, S Coluzzi, C Damico, G di Giorgio, B Monarca
Source: Haematologica. 1990 Mar-Apr
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