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Innate immune defences are essential for the control of virus infection and are triggered through host recognition of viral macromolecular motifs know…
Authors: Takeshi Saito, David M Owen, Fuguo Jiang, Joseph Marcotrigiano, Michael Gale
Source: Nature. 2008 Jul 24
View Full TextA wide variety of stimuli induce the inflammasome, but little is known about its role in immune protection against viruses. In this issue of Immunity,…
Authors: David M Owen, Michael Gale
Source: Immunity. 2009 Apr 17
View Full TextOn the bicentennial of Darwin's birth, we describe the origin of the calcar avis and summarize the debate around this structure, which played a centra…
Authors: Christopher M Owen, Allyson Howard, Devin K Binder
Source: Neurosurgery. 2009 Dec
View Full TextThe bacterial transposon Tn7 directs transposition into actively replicating DNA by a mechanism involving the transposon-encoded protein TnsE. Here we…
Authors: Adam R Parks, Zaoping Li, Qiaojuan Shi, Roisin M Owens, Moonsoo M Jin, Joseph E Peters
Source: Cell. 2009 Aug 21
View Full TextAuthors: David M Owens
Source: Nature genetics. 2009 Oct
View Full TextThe basal ganglia as a whole are broadly responsible for sensorimotor coordination, including response selection and initiation. However, it has becom…
Authors: Jessica A Grahn, John A Parkinson, Adrian M Owen
Source: Progress in neurobiology. 2008 Nov
View Full TextThe sirtuin gene family (SIRT) is hypothesized to regulate the aging process and play a role in cellular repair. This work demonstrates that SIRT3(-/-…
Authors: Hyun-Seok Kim, Krish Patel, Kristi Muldoon-Jacobs, Kheem S Bisht, Nukhet Aykin-Burns, J Daniel Pennington, Riet van der Meer, Phuongmai Nguyen, Jason Savage, Kjerstin M Owens,…
Source: Cancer cell. 2010 Jan 19
View Full TextBACKGROUND: Conventional whole-body MRI at 1.5 T does not provide adequate image quality of small fetuses, thus reducing its potential for use as an a…
Authors: Sudhin Thayyil, Jon O Cleary, Neil J Sebire, Rosemary J Scott, Kling Chong, Roxanna Gunny, Catherine M Owens, Oystein E Olsen, Amaka C Offiah, Harold G Parks,…
Source: Lancet. 2009 Aug 8
View Full TextHost cell barriers to the early phase of immunodeficiency virus replication explain the current distribution of these viruses among human and non-huma…
Authors: Matthew Stremlau, Christopher M Owens, Michel J Perron, Michael Kiessling, Patrick Autissier, Joseph Sodroski
Source: Nature. 2004 Feb 26
View Full TextIsoprene, monoterpenes and sesquiterpenes are synthesized and emitted by some plant species, but not all plant species have this ability. These volati…
Authors: Susan M Owen, Josep PeƱuelas
Source: Trends in plant science. 2005 Sep
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