1 to 10 of 325 literature results

• Annihilating host defense.

  Authors: M M Frank

  Source: Nature medicine. 2001 Dec

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• Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent.

  Alternative human and non-human Ad serotype vectors are currently studied for gene therapy and/or vaccine applications to capitalize upon their likely…

  Authors: D M Appledorn, A Kiang, A McBride, H Jiang, S Seregin, J M Scott, R Stringer, Y Kousa, M Hoban, M M Frank,…

  Source: Gene therapy. 2008 Jun

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• Effectiveness of adalimumab in treating patients with active psoriatic arthritis and predictors of good clinical responses for arthritis, skin and nail lesions.

  OBJECTIVES: To evaluate the effectiveness of adalimumab in patients with psoriatic arthritis (PsA) and identify predictors of good clinical response f…

  Authors: F Van den Bosch, B Manger, P Goupille, N McHugh, E Rødevand, P Holck, R F van Vollenhoven, M Leirisalo-Repo, O Fitzgerald, M Kron,…

  Source: Annals of the rheumatic diseases. 2010 Feb

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• Complement activation influences Staphylococcus aureus adherence to endothelial cells.

  The ability of Staphylococcus aureus to adhere to endothelial cells (EC) is a critical step in the development of metastatic infection. The role of co…

  Authors: K M Cunnion, M M Frank

  Source: Infection and immunity. 2003 Mar

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• Availability of complement bound to Staphylococcus aureus to interact with membrane complement receptors influences efficiency of phagocytosis.

  Complement-mediated opsonization of encapsulated Staphylococcus aureus (CP+) of the predominant capsule types, 5 and 8, remains poorly understood. Our…

  Authors: K M Cunnion, H-M Zhang, M M Frank

  Source: Infection and immunity. 2003 Feb

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• Pathologic fracture of the distal femur in total knee arthroplasty. Polyethylene-wear-induced osteolysis? A case report

  Malignant bone tumors and osteitis of the distal femur are common at every age. These conditions must be considered in patients with total knee arthro…

  Authors: M Napp, M Frank, M Witt

  Source: Der Orthopäde. 2009 Oct

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• Capsule production and growth phase influence binding of complement to Staphylococcus aureus.

  Complement-mediated opsonization of bacteria by C3 binding is an important component of the host innate immune system. Little information is available…

  Authors: K M Cunnion, J C Lee, M M Frank

  Source: Infection and immunity. 2001 Nov

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• Complement deficiencies.

  The complement proteins play an important role in innate immunity, promoting inflammation and microbial killing. They play a role in the adaptive immu…

  Authors: M M Frank

  Source: Pediatric clinics of North America. 2000 Dec

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• The mechanism by which microorganisms avoid complement attack.

  The complement system provides a critical level of defense against bacterial invasion. Various microorganisms have evolved a variety of mechanisms to …

  Authors: M M Frank

  Source: Current opinion in immunology. 1992 Feb

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• 2,3,7,8-tetrachlorodibenzo-p-dioxin and natural immunity: lack of an effect on the complement system in a guinea pig model.

  We examined the complement system as a potential target for toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in normal Hartley guinea pigs. Guin…

  Authors: E Wagner, M M Frank, R J Smialowicz

  Source: Toxicology. 2001 Feb 21

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