1 to 6 of 6 literature results

• Embryonic fibroblasts from mice lacking Tgif were defective in cell cycling.

  Holoprosencephaly (HPE) is the most common structural anomaly of the human brain, resulting from incomplete cleavage of the developing forebrain durin…

  Authors: Lynn Mar, Pamela A Hoodless

  Source: Molecular and cellular biology. 2006 Jun

  View Free Full Text

• The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region.

  Imprinted genes are commonly clustered in domains across the mammalian genome, suggesting a degree of coregulation via long-range coordination of thei…

  Authors: Louis Lefebvre, Lynn Mar, Aaron Bogutz, Rosemary Oh-McGinnis, Mohammad A Mandegar, Jana Paderova, Marina Gertsenstein, Jeremy A Squire, Andras Nagy

  Source: Human molecular genetics. 2009 Nov 15

  View Full Text

• Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.

  The distal end of mouse chromosome 7 (Chr 7) contains a large cluster of imprinted genes. In this region two cis-acting imprinting centers, IC1 (H19 D…

  Authors: Rosemary Oh, Rita Ho, Lynn Mar, Marina Gertsenstein, Jana Paderova, John Hsien, Jeremy A Squire, Michael J Higgins, Andras Nagy, Louis Lefebvre

  Source: Molecular and cellular biology. 2008 Feb

  View Free Full Text

• Creation and use of a cre recombinase transgenic database.

  In many cases, a gene "knockout" results in early embryonic lethality, which obscures the study of potential later functions. In other cases, the "kno…

  Authors: Andras Nagy, Lynn Mar, Graham Watts

  Source: Methods in molecular biology (Clifton, N.J.). 2009

  View Full Text

• A genetic screen for mutations that affect cranial nerve development in the mouse.

  Cranial motor and sensory nerves arise stereotypically in the embryonic hindbrain, act as sensitive indicators of general and region-specific neuronal…

  Authors: Lynn Mar, Elena Rivkin, Dennis Y Kim, Joanna Y Yu, Sabine P Cordes

  Source: The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005 Dec 14

  View Full Text

• Analysis of hindbrain patterning defects caused by the kreisler(enu) mutation reveals multiple roles of Kreisler in hindbrain segmentation.

  The embryonic hindbrain is subdivided into eight subunits, termed rhombomeres (r1-r8). The Kreisler (Krml1/MafB/val) transcription factor is expressed…

  Authors: Virginia S Sadl, Angela Sing, Lynn Mar, Fuzi Jin, Sabine P Cordes

  Source: Developmental dynamics : an official publication of the American Association of Anatomists. 2003 May

  View Full Text