1 to 6 of 6 literature results

• Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.

  Imatinib mesylate (Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous leukemia. Here we rep…

  Authors: Risto Kerkelä, Luanda Grazette, Rinat Yacobi, Cezar Iliescu, Richard Patten, Cara Beahm, Brian Walters, Sergei Shevtsov, Stéphanie Pesant, Fred J Clubb,…

  Source: Nature medicine. 2006 Aug

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• Higher frequency of high-grade rejections in cardiac allograft patients after Quilty B lesions or grade 2/4 rejections.

  BACKGROUND: To better understand how different histologic patterns of allograft inflammation found on biopsies of human cardiac allografts progress to…

  Authors: R Neal Smith, Yuchiao Chang, Stuart Houser, G William Dec, Luanda Grazette

  Source: Transplantation. 2002 Jun 27

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• C4d deposition in cardiac allografts correlates with alloantibody.

  BACKGROUND: The presence of C4d along the peritubular capillaries in kidney allografts correlates with the presence of anti-donor serum alloantibodies…

  Authors: Rex Neal Smith, Nicole Brousaides, Luanda Grazette, Susan Saidman, Marc Semigran, Thomas Disalvo, Joren Madsen, G William Dec, Antonio R Perez-Atayde, A Bernard Collins

  Source: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2005 Sep

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• Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle.

  The ability to image cardiomyocyte apoptosis in vivo with high-resolution MRI could facilitate the development of novel cardioprotective therapies. Th…

  Authors: David E Sosnovik, Eyk A Schellenberger, Matthias Nahrendorf, Mikhail S Novikov, Takashi Matsui, George Dai, Fred Reynolds, Luanda Grazette, Anthony Rosenzweig, Ralph Weissleder,…

  Source: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2005 Sep

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• Cardiac-specific gene expression facilitated by an enhanced myosin light chain promoter.

  BACKGROUND: Adenoviral gene transfer has been shown to be effective in cardiac myocytes in vitro and in vivo. A major limitation of myocardial gene th…

  Authors: Wolfgang Boecker, Oliver Y Bernecker, Joseph C Wu, Xinsheng Zhu, Tomohiro Sawa, Luanda Grazette, Anthony Rosenzweig, Federica del Monte, Ulrich Schmidt, Roger J Hajjar

  Source: Molecular imaging : official journal of the Society for Molecular Imaging. 2004 Apr

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• PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury.

  Acute activation of the serine-threonine kinase Akt is cardioprotective and reduces both infarction and dysfunction after ischemia/reperfusion injury …

  Authors: Tomohisa Nagoshi, Takashi Matsui, Takuma Aoyama, Annarosa Leri, Piero Anversa, Ling Li, Wataru Ogawa, Federica del Monte, Judith K Gwathmey, Luanda Grazette,…

  Source: The Journal of clinical investigation. 2005 Aug

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