1 to 10 of 48 literature results

• The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism.

  Glucose homeostasis is regulated systemically by hormones such as insulin and glucagon, and at the cellular level by energy status. Glucagon enhances …

  Authors: Seung-Hoi Koo, Lawrence Flechner, Ling Qi, Xinmin Zhang, Robert A Screaton, Shawn Jeffries, Susan Hedrick, Wu Xu, Fayçal Boussouar, Paul Brindle,…

  Source: Nature. 2005 Oct 20

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• Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation.

  Telomeres protect chromosome ends from fusion, degradation and recombination. Loss of telomere function has opposite effects on tumorigenesis: apoptos…

  Authors: Ling Qi, Margaret A Strong, Baktiar O Karim, David L Huso, Carol W Greider

  Source: Nature cell biology. 2005 Jul

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• Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.

  Nuclear dysfunction is a key feature of the pathology of polyglutamine (polyQ) diseases. It has been suggested that mutant polyQ proteins impair funct…

  Authors: Mei-Ling Qi, Kazuhiko Tagawa, Yasushi Enokido, Natsue Yoshimura, Yo-ichi Wada, Kei Watase, Sho-ichi Ishiura, Ichiro Kanazawa, Juan Botas, Minoru Saitoe,…

  Source: Nature cell biology. 2007 Apr

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• Microfluidics with on-line dynamic light scattering for size measurements.

  We present a detailed investigation on the feasibility of on-line dynamic light scattering measurements of colloidal sizes in a pressure-driven microf…

  Authors: Fanny Destremaut, Jean-Baptiste Salmon, Ling Qi, Jean-Paul Chapel

  Source: Lab on a chip. 2009 Nov 21

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• Development of a group selective molecularly imprinted polymers based solid phase extraction of malachite green from fish water and fish feed samples.

  A group selective molecularly imprinted solid phase extraction (MISPE) for malachite green (MG) from fish water and fish feed samples was developed. U…

  Authors: Ya-hui Li, Tao Yang, Xiao-ling Qi, Yu-wei Qiao, An-ping Deng

  Source: Analytica chimica acta. 2008 Aug 29

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• Expression of human PQBP-1 in Drosophila impairs long-term memory and induces abnormal courtship.

  Frame shift mutations of the polyglutamine binding protein-1 (PQBP1) gene lead to total or partial truncation of the C-terminal domain (CTD) and cause…

  Authors: Natsue Yoshimura, Daisuke Horiuchi, Masao Shibata, Minoru Saitoe, Mei-Ling Qi, Hitoshi Okazawa

  Source: FEBS letters. 2006 Apr 17

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• Oxygen-glucose deprivation activates 5-lipoxygenase mediated by oxidative stress through the p38 mitogen-activated protein kinase pathway in PC12 cells.

  5-Lipoxygenase (5-LOX) is a key enzyme catalyzing arachidonic acid to form leukotrienes. We have reported that ischemic-like injury activates 5-LOX in…

  Authors: Cheng-Tan Li, Wei-Ping Zhang, Yun-Bi Lu, San-Hua Fang, Yu-Mei Yuan, Ling-Ling Qi, Li-Hui Zhang, Xiao-Jia Huang, Lei Zhang, Zhong Chen,…

  Source: Journal of neuroscience research. 2009 Mar

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• Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis.

  To examine the role of ataxia-telangiectasia mutated (Atm) in telomere function, we generated Atm and telomerase null mice (Atm(-/-) mTR(-/-) iG6 mice…

  Authors: Ling Qi, Margaret A Strong, Baktiar O Karim, Mary Armanios, David L Huso, Carol W Greider

  Source: Cancer research. 2003 Dec 1

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• Hepatoma-derived growth factor, a new trophic factor for motor neurons, is up-regulated in the spinal cord of PQBP-1 transgenic mice before onset of degeneration.

  Hepatoma-derived growth factor (HDGF) is a nuclear protein homologous to the high-mobility group B1 family of proteins. It is known to be released fro…

  Authors: Shigeki Marubuchi, Tomohiro Okuda, Kazuhiko Tagawa, Yasushi Enokido, Daisuke Horiuchi, Reiko Shimokawa, Takuya Tamura, Mei-Ling Qi, Yoshinobu Eishi, Kazuhiko Watabe,…

  Source: Journal of neurochemistry. 2006 Oct

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• Characterizing blood volume fraction (BVF) in a VX2 tumor.

  OBJECTIVES: Neovascular proliferation of a tumor's blood supply is an important precursor of malignant growth. Evaluation of blood volume may provide …

  Authors: Xiu-Ling Qi, Peter Burns, Juimiin Hong, Jeff Stainsby, Graham Wright

  Source: Magnetic resonance imaging. 2008 Feb

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