1 to 7 of 7 literature results

• A survey of genetic human cortical gene expression.

  It is widely assumed that genetic differences in gene expression underpin much of the difference among individuals and many of the quantitative traits…

  Authors: Amanda J Myers, J Raphael Gibbs, Jennifer A Webster, Kristen Rohrer, Alice Zhao, Lauren Marlowe, Mona Kaleem, Doris Leung, Leslie Bryden, Priti Nath,…

  Source: Nature genetics. 2007 Dec

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• Genetic control of human brain transcript expression in Alzheimer disease.

  We recently surveyed the relationship between the human brain transcriptome and genome in a series of neuropathologically normal postmortem samples. W…

  Authors: Jennifer A Webster, J Raphael Gibbs, Jennifer Clarke, Monika Ray, Weixiong Zhang, Peter Holmans, Kristen Rohrer, Alice Zhao, Lauren Marlowe, Mona Kaleem,…

  Source: American journal of human genetics. 2009 Apr

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• GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.

  The apolipoprotein E (APOE) epsilon4 allele is the best established genetic risk factor for late-onset Alzheimer's disease (LOAD). We conducted genome…

  Authors: Eric M Reiman, Jennifer A Webster, Amanda J Myers, John Hardy, Travis Dunckley, Victoria L Zismann, Keta D Joshipura, John V Pearson, Diane Hu-Lince, Matthew J Huentelman,…

  Source: Neuron. 2007 Jun 7

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• The structure of the tau haplotype in controls and in progressive supranuclear palsy.

  The group of neurodegenerative diseases collectively known as tauopathies are characterized by hallmark lesions consisting of fibrillar aggregates of …

  Authors: Alan M Pittman, Amanda J Myers, Jaime Duckworth, Leslie Bryden, Melissa Hanson, Patrick Abou-Sleiman, Nicholas W Wood, John Hardy, Andrew Lees, Rohan de Silva

  Source: Human molecular genetics. 2004 Jun 15

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• Sorl1 as an Alzheimer's disease predisposition gene?

  Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressively disabling impairments in memory, cognition, and non-cognitive …

  Authors: Jennifer A Webster, Amanda J Myers, John V Pearson, David W Craig, Diane Hu-Lince, Keith D Coon, Victoria L Zismann, Thomas Beach, Doris Leung, Leslie Bryden,…

  Source: Neuro-degenerative diseases. 2008

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• A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.

  OBJECTIVE: While the apolipoprotein E (APOE) epsilon allele is a well-established risk factor for late-onset Alzheimer's disease (AD), initial genome …

  Authors: Keith D Coon, Amanda J Myers, David W Craig, Jennifer A Webster, John V Pearson, Diane Hu Lince, Victoria L Zismann, Thomas G Beach, Doris Leung, Leslie Bryden,…

  Source: The Journal of clinical psychiatry. 2007 Apr

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• Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.

  Linkage studies have suggested there is a susceptibility gene for late onset Alzheimer's disease (LOAD) in a broad region of chromosome 10. A strong p…

  Authors: Petra Nowotny, Anthony L Hinrichs, Scott Smemo, John S K Kauwe, Taylor Maxwell, Peter Holmans, Marian Hamshere, Dragana Turic, Luke Jehu, Paul Hollingworth,…

  Source: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2005 Jul 5

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