1 to 10 of 15 literature results

• Bioreactor expansion of human neural precursor cells in serum-free media retains neurogenic potential.

  Human neural precursor cells (hNPCs), harvested from somatic tissue and grown in vitro, may serve as a source of cells for cell replacement strategies…

  Authors: Behnam A Baghbaderani, Karim Mukhida, Arindom Sen, Michael S Kallos, Murray Hong, Ivar Mendez, Leo A Behie

  Source: Biotechnology and bioengineering. 2010 Mar 1

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• Dynamic behavior of cells within neurospheres in expanding populations of neural precursors.

  Large-scale expansion of neural stem and progenitor cells will be essential for clinically treating the large number of patients suffering from neurod…

  Authors: Tony Y Wang, Arindom Sen, Leo A Behie, Michael S Kallos

  Source: Brain research. 2006 Aug 30

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• Expansion of human neural precursor cells in large-scale bioreactors for the treatment of neurodegenerative disorders.

  The transplantation of in vitro expanded human neural precursor cells (hNPCs) represents a potential new treatment alternative for individuals sufferi…

  Authors: Behnam A Baghbaderani, Leo A Behie, Arindom Sen, Karim Mukhida, Murray Hong, Ivar Mendez

  Source: Biotechnology progress. 2008 Jul-Aug

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• Scaled-up production of mammalian neural precursor cell aggregates in computer-controlled suspension bioreactors.

  The clinical use of neural precursor cells (NPCs) for the treatment of neurological diseases, such as Parkinson's disease and Huntington's disease, re…

  Authors: Jane A Gilbertson, Arindom Sen, Leo A Behie, Michael S Kallos

  Source: Biotechnology and bioengineering. 2006 Jul 5

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• New tissue dissociation protocol for scaled-up production of neural stem cells in suspension bioreactors.

  The successful dissociation of mammalian neural stem cell (NSC) aggregates (neurospheres) into a single-cell suspension is an important procedure when…

  Authors: Arindom Sen, Michael S Kallos, Leo A Behie

  Source: Tissue engineering. 2004 May-Jun

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• Characterization of human islet-like structures generated from pancreatic precursor cells in culture.

  This study addresses the characterization of human islet-like structures generated from a newly discovered sparse population of precursor cells (Petro…

  Authors: Cheryl A Bodnar, Arindom Sen, Michael S Kallos, Leo A Behie, Maria Petropavlovskaia, Lawrence Rosenberg

  Source: Biotechnology and bioengineering. 2006 Apr 5

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• Scale-up of breast cancer stem cell aggregate cultures to suspension bioreactors.

  It has been hypothesized that breast tumor formation results from the activity of a scarce population of cells known as Breast Cancer Stem Cells (BrCS…

  Authors: Benjamin S Youn, Arindom Sen, Leo A Behie, Adele Girgis-Gabardo, John A Hassell

  Source: Biotechnology progress. 2006 May-Jun

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• Optimization of reovirus production from mouse L-929 cells in suspension culture.

  Reovirus serotype 3 Dearing (T3D) has shown potential as a novel cancer therapy. To support the increasing demand for reovirus, a two-stage perfusion …

  Authors: Sunghoon Jung, Leo A Behie, Patrick W K Lee, Patrick J Farrell

  Source: Biotechnology and bioengineering. 2004 Mar 30

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• Cell cycle kinetics of expanding populations of neural stem and progenitor cells in vitro.

  Neural stem cells (NSCs) are undifferentiated, primitive cells with important potential applications including the replacement of neural tissue lost d…

  Authors: Sharmila Alam, Arindom Sen, Leo A Behie, Michael S Kallos

  Source: Biotechnology and bioengineering. 2004 Nov 5

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• Production of islet-like structures from neonatal porcine pancreatic tissue in suspension bioreactors.

  The aim of this study was to develop a scaleable process to expand pancreatic endocrine tissue (i.e., aggregates or islet-like structures) in suspensi…

  Authors: Meera Chawla, Cheryl A Bodnar, Arindom Sen, Michael S Kallos, Leo A Behie

  Source: Biotechnology progress. 2006 Mar-Apr

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