10 literature results

• A survey of genetic human cortical gene expression.

  It is widely assumed that genetic differences in gene expression underpin much of the difference among individuals and many of the quantitative traits…

  Authors: Amanda J Myers, J Raphael Gibbs, Jennifer A Webster, Kristen Rohrer, Alice Zhao, Lauren Marlowe, Mona Kaleem, Doris Leung, Leslie Bryden, Priti Nath,…

  Source: Nature genetics. 2007 Dec

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• Genetic control of human brain transcript expression in Alzheimer disease.

  We recently surveyed the relationship between the human brain transcriptome and genome in a series of neuropathologically normal postmortem samples. W…

  Authors: Jennifer A Webster, J Raphael Gibbs, Jennifer Clarke, Monika Ray, Weixiong Zhang, Peter Holmans, Kristen Rohrer, Alice Zhao, Lauren Marlowe, Mona Kaleem,…

  Source: American journal of human genetics. 2009 Apr

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• GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.

  The apolipoprotein E (APOE) epsilon4 allele is the best established genetic risk factor for late-onset Alzheimer's disease (LOAD). We conducted genome…

  Authors: Eric M Reiman, Jennifer A Webster, Amanda J Myers, John Hardy, Travis Dunckley, Victoria L Zismann, Keta D Joshipura, John V Pearson, Diane Hu-Lince, Matthew J Huentelman,…

  Source: Neuron. 2007 Jun 7

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• Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.

  Several studies have reported evidence for linkage of late-onset Alzheimer's disease (LOAD) to chromosome 9. Recently, an intronic polymorphism affect…

  Authors: Scott Smemo, Petra Nowotny, Anthony L Hinrichs, John S K Kauwe, Sara Cherny, Katherine Erickson, Amanda J Myers, Mona Kaleem, Lauren Marlowe, Alison M Gibson,…

  Source: Annals of neurology. 2006 Jan

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• The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts.

  Previously we have shown that the H1c haplotype on the background of the H1 clade of haplotypes at the MAPT locus is associated with increased risk fo…

  Authors: Amanda J Myers, Alan M Pittman, Alice S Zhao, Kristen Rohrer, Mona Kaleem, Lauren Marlowe, Andrew Lees, Doris Leung, Ian G McKeith, Robert H Perry,…

  Source: Neurobiology of disease. 2007 Mar

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• Blood culture contamination rates after skin antisepsis with chlorhexidine gluconate versus povidone-iodine in a pediatric emergency department.

  OBJECTIVE: To determine blood culture contamination rates after skin antisepsis with chlorhexidine, compared with povidone-iodine. DESIGN: Retrospecti…

  Authors: Lauren Marlowe, Rakesh D Mistry, Susan Coffin, Kateri H Leckerman, Karin L McGowan, Dingwei Dai, Louis M Bell, Theoklis Zaoutis

  Source: Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America. 2010 Feb

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• Association of rapid head growth in children following tracheostomy tube placement.

  INTRODUCTION: Our clinical observation indicates that some children who have a tracheostomy may experience increasing head circumference as they grow …

  Authors: Allison Thompson, Daniela H Davis, Troy E Dominguez, Steven Schultz, Lauren Marlowe, Jimmy W Huh, Mark A Helfaer

  Source: Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners. 2009 Sep-Oct

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• Insulin-degrading enzyme haplotypes affect insulin levels but not dementia risk.

  BACKGROUND: Insulin-degrading enzyme (IDE) polymorphism is hypothesized to regulate insulin levels as well as processes involved in neuronal compromis…

  Authors: Lauren Marlowe, Rita Peila, Kelly Suzanne Benke, John Hardy, Lon R White, Lenore J Launer, Amanda Myers

  Source: Neuro-degenerative diseases. 2006

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• Sorl1 as an Alzheimer's disease predisposition gene?

  Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressively disabling impairments in memory, cognition, and non-cognitive …

  Authors: Jennifer A Webster, Amanda J Myers, John V Pearson, David W Craig, Diane Hu-Lince, Keith D Coon, Victoria L Zismann, Thomas Beach, Doris Leung, Leslie Bryden,…

  Source: Neuro-degenerative diseases. 2008

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• A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.

  OBJECTIVE: While the apolipoprotein E (APOE) epsilon allele is a well-established risk factor for late-onset Alzheimer's disease (AD), initial genome …

  Authors: Keith D Coon, Amanda J Myers, David W Craig, Jennifer A Webster, John V Pearson, Diane Hu Lince, Victoria L Zismann, Thomas G Beach, Doris Leung, Leslie Bryden,…

  Source: The Journal of clinical psychiatry. 2007 Apr

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