1 to 10 of 21 literature results

• A genome-wide linkage and association scan reveals novel loci for autism.

  Although autism is a highly heritable neurodevelopmental disorder, attempts to identify specific susceptibility genes have thus far met with limited s…

  Authors: Lauren A Weiss, Dan E Arking, Gene Discovery Project of Johns Hopkins & the Autism Consortium, Mark J Daly, Aravinda Chakravarti

  Source: Nature. 2009 Oct 8

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• The sex-specific genetic architecture of quantitative traits in humans.

  Mapping genetically complex traits remains one of the greatest challenges in human genetics today. In particular, gene-environment and gene-gene inter…

  Authors: Lauren A Weiss, Lin Pan, Mark Abney, Carole Ober

  Source: Nature genetics. 2006 Feb

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• Sex-specific genetic architecture of whole blood serotonin levels.

  Recently, a quantitative-trait locus (QTL) for whole blood serotonin level was identified in a genomewide linkage and association study in a founder p…

  Authors: Lauren A Weiss, Mark Abney, Edwin H Cook, Carole Ober

  Source: American journal of human genetics. 2005 Jan

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• Identification of EFHC2 as a quantitative trait locus for fear recognition in Turner syndrome.

  One-third of women with Turner syndrome (45,X) have autism-like social and communication difficulties, despite normal verbal IQ. Deletion mapping of t…

  Authors: Lauren A Weiss, Shaun Purcell, Skye Waggoner, Kate Lawrence, David Spektor, Mark J Daly, Pamela Sklar, David Skuse

  Source: Human molecular genetics. 2007 Jan 1

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• Disruption of neurexin 1 associated with autism spectrum disorder.

  Autism is a neurodevelopmental disorder of complex etiology in which genetic factors play a major role. We have implicated the neurexin 1 (NRXN1) gene…

  Authors: Hyung-Goo Kim, Shotaro Kishikawa, Anne W Higgins, Ihn-Sik Seong, Diana J Donovan, Yiping Shen, Eric Lally, Lauren A Weiss, Juliane Najm, Kerstin Kutsche,…

  Source: American journal of human genetics. 2008 Jan

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• ITGB3 shows genetic and expression interaction with SLC6A4.

  Autism affects more males than females and is associated with disturbances of the serotonin system. The integrin beta3 (ITGB3) and serotonin transport…

  Authors: Lauren A Weiss, Carole Ober, Edwin H Cook

  Source: Human genetics. 2006 Aug

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• Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations.

  RATIONALE: Recent genetic studies have implicated integrins in asthma and atopy susceptibility. We therefore evaluated the integrin-beta3 gene (ITGB3)…

  Authors: Lauren A Weiss, Lucille A Lester, James E Gern, Raoul L Wolf, Rodney Parry, Robert F Lemanske, Julian Solway, Carole Ober

  Source: American journal of respiratory and critical care medicine. 2005 Jul 1

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• Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample.

  A recent genome-scan identified the Leu33Pro polymorphism in the beta3 integrin (ITGB3) gene as a quantitative trait locus for whole blood serotonin l…

  Authors: Lauren A Weiss, Mark Abney, Rodney Parry, Angelo M Scanu, Edwin H Cook, Carole Ober

  Source: Human genetics. 2005 Jun

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• Preliminary evidence of association between EFHC2, a gene implicated in fear recognition, and harm avoidance.

  Genetic variation at the EF-hand domain containing 2 gene (EFHC2) locus has been associated with fear recognition in Turner syndrome. The aim of this …

  Authors: Carolina Blaya, Priya Moorjani, Giovanni Abrahão Salum, Leonardo Gonçalves, Lauren A Weiss, Sandra Leistner-Segal, Gisele G Manfro, Jordan W Smoller

  Source: Neuroscience letters. 2009 Mar 6

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• Autism genetics: emerging data from genome-wide copy-number and single nucleotide polymorphism scans.

  Autism and related traits are highly heritable but cannot be explained by currently known genetic risk factors. Therefore, the advent of genome-wide s…

  Authors: Lauren A Weiss

  Source: Expert review of molecular diagnostics. 2009 Nov

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