1 to 8 of 8 literature results

• Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors.

  Nuclear receptors undergo ligand-dependent conformational changes that are required for corepressor-coactivator exchange, but whether there is an actu…

  Authors: Ivan Garcia-Bassets, Young-Soo Kwon, Francesca Telese, Gratien G Prefontaine, Kasey R Hutt, Christine S Cheng, Bong-Gun Ju, Kenneth A Ohgi, Jianxun Wang, Laure Escoubet-Lozach,…

  Source: Cell. 2007 Feb 9

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• Pomalidomide and lenalidomide induce p21 WAF-1 expression in both lymphoma and multiple myeloma through a LSD1-mediated epigenetic mechanism.

  Lenalidomide and pomalidomide have both been evaluated clinically for their properties as anticancer agents, with lenalidomide being available commerc…

  Authors: Laure Escoubet-Lozach, I-Lin Lin, Kristen Jensen-Pergakes, Helen A Brady, Anita K Gandhi, Peter H Schafer, George W Muller, Peter J Worland, Kyle W H Chan, Dominique Verhelle

  Source: Cancer research. 2009 Sep 15

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• Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression.

  The proto-oncogene c-Myc plays a central role in cell growth and the development of human tumors. c-Myc interacts with Max and Myc-Max complexes bind …

  Authors: Kazuhito Toyo-oka, Timothy J Bowen, Shinji Hirotsune, Zirong Li, Sonia Jain, Sara Ota, Laure Escoubet-Lozach, Laure Escoubet Lozach, Ivan Garcia-Bassets, Ivan Garcia Bassett,…

  Source: Cancer research. 2006 Jun 1

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• Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS.

  The molecular mechanisms that control the proliferation and differentiation of specific cell types remain poorly understood. Positive ETS factors play…

  Authors: Kelly D Hester, Dominique Verhelle, Laure Escoubet-Lozach, Rosa Luna, David W Rose, Christopher K Glass

  Source: Cell cycle (Georgetown, Tex.). 2007 Jul 1

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• n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells.

  Polyunsaturated fatty acids (PUFA) n-3 inhibit inflammation, in vivo and in vitro in keratinocytes. We examined in HaCaT keratinocyte cell line whethe…

  Authors: Gérald Chêne, Marc Dubourdeau, Patricia Balard, Laure Escoubet-Lozach, Claudine Orfila, Antoine Berry, José Bernad, Marie-Françoise Aries, Marie Charveron, Bernard Pipy

  Source: Biochimica et biophysica acta. 2007 May

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• The role of transcription factors in allergic inflammation.

  The induction of allergic inflammation and the expression of allergic disorders are dependent on the coordinated regulation of numerous genes. The pro…

  Authors: Laure Escoubet-Lozach, Christopher K Glass, Stephen I Wasserman

  Source: The Journal of allergy and clinical immunology. 2002 Oct

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• PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation.

  The molecular mechanisms involved in regulating the balance between cellular proliferation and differentiation remain poorly understood. Members of th…

  Authors: Dominique Sawka-Verhelle, Laure Escoubet-Lozach, Amy L Fong, Kelly D Hester, Stephan Herzig, Patricia Lebrun, Christopher K Glass

  Source: The Journal of biological chemistry. 2004 Apr 23

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• TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism.

  The diverse functions of macrophages as participants in innate and acquired immune responses are regulated by the specific milieu of environmental fac…

  Authors: John S Welch, Laure Escoubet-Lozach, David B Sykes, Kate Liddiard, David R Greaves, Christopher K Glass

  Source: The Journal of biological chemistry. 2002 Nov 8

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