1 to 4 of 4 literature results

• Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses.

  Sterol metabolism has recently been linked to innate and adaptive immune responses through liver X receptor (LXR) signaling. Whether products of stero…

  Authors: Eduardo J Villablanca, Laura Raccosta, Dan Zhou, Raffaella Fontana, Daniela Maggioni, Aurora Negro, Francesca Sanvito, Maurilio Ponzoni, Barbara Valentinis, Marco Bregni,…

  Source: Nature medicine. 2010 Jan

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• Peripheral blood lymphocytes genetically modified to express the self/tumor antigen MAGE-A3 induce antitumor immune responses in cancer patients.

  Dendritic cell (DC) targeting in vivo has recently been shown to confer strong and protective cytotoxic T lymphocyte (CTL)-based immunity in tumor mur…

  Authors: Raffaella Fontana, Marco Bregni, Arcadi Cipponi, Laura Raccosta, Cristina Rainelli, Daniela Maggioni, Francesca Lunghi, Fabio Ciceri, Sylvain Mukenge, Claudio Doglioni,…

  Source: Blood. 2009 Feb 19

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• Selected natural and synthetic retinoids impair CCR7- and CXCR4-dependent cell migration in vitro and in vivo.

  Dendritic cell (DC) migration to secondary lymphoid organs is a crucial step to initiate adaptive immune responses. This step requires the expression …

  Authors: Eduardo J Villablanca, Dan Zhou, Barbara Valentinis, Aurora Negro, Laura Raccosta, Laura Mauri, Alessandro Prinetti, Sandro Sonnino, Claudio Bordignon, Catia Traversari,…

  Source: Journal of leukocyte biology. 2008 Sep

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• Lymphocytes genetically modified to express tumor antigens target DCs in vivo and induce antitumor immunity.

  The exploitation of the physiologic processing and presenting machinery of DCs by in vivo loading of tumor-associated antigens may improve the immunog…

  Authors: Vincenzo Russo, Arcadi Cipponi, Laura Raccosta, Cristina Rainelli, Raffaella Fontana, Daniela Maggioni, Francesca Lunghi, Sylvain Mukenge, Fabio Ciceri, Marco Bregni,…

  Source: The Journal of clinical investigation. 2007 Oct

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