1 to 8 of 8 literature results

• Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.

  Charcot-Marie-Tooth (CMT) neuropathies are common disorders of the peripheral nervous system caused by demyelination or axonal degeneration, or a comb…

  Authors: Albena Jordanova, Joy Irobi, Florian P Thomas, Patrick Van Dijck, Kris Meerschaert, Maarten Dewil, Ines Dierick, An Jacobs, Els De Vriendt, Velina Guergueltcheva,…

  Source: Nature genetics. 2006 Feb

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• The tandem PDZ protein Syntenin interacts with the aminoacyl tRNA synthetase complex in a lysyl-tRNA synthetase-dependent manner.

  Syntenin-1 is a tandem PDZ protein that binds a diverse array of signaling molecules that are often associated with cell adhesion and intracellular tr…

  Authors: Kris Meerschaert, Eline Remue, Ariane De Ganck, An Staes, Ciska Boucherie, Kris Gevaert, Joël Vandekerckhove, Lawrence Kleiman, Jan Gettemans

  Source: Journal of proteome research. 2008 Nov

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• PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane.

  PDZ proteins organize multiprotein signaling complexes. According to current views, PDZ domains engage in protein-protein interactions. Here we show t…

  Authors: Pascale Zimmermann, Kris Meerschaert, Gunter Reekmans, Iris Leenaerts, J Victor Small, Joël Vandekerckhove, Guido David, Jan Gettemans

  Source: Molecular cell. 2002 Jun

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• The tandem PDZ domains of syntenin promote cell invasion.

  Syntenin is a tandem PDZ protein that has recently been shown to be overexpressed in several cancer cells and tissues, and that might play an active r…

  Authors: Kris Meerschaert, Erik Bruyneel, Olivier De Wever, Berlinda Vanloo, Ciska Boucherie, Marc Bracke, Joël Vandekerckhove, Jan Gettemans

  Source: Experimental cell research. 2007 May 15

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• Lysophosphatidic acid affinity chromatography reveals pyruvate kinase as a specific LPA-binding protein.

  Lysophosphatidic acid is a pleiotropic lipid signaling molecule that evokes a broad array of cellular responses including proliferation, tumor cell in…

  Authors: Sophie Desmaret, Lian Qian, Berlinda Vanloo, Kris Meerschaert, Jozef Van Damme, Johan Grooten, Joël Vandekerckhove, Glenn D Prestwich, Jan Gettemans

  Source: Biological chemistry. 2005 Nov

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• The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain.

  Zonula occludens proteins (ZO) are postsynaptic density protein-95 discs large-zonula occludens (PDZ) domain-containing proteins that play a fundament…

  Authors: Kris Meerschaert, Moe Phyu Tun, Eline Remue, Ariane De Ganck, Ciska Boucherie, Berlinda Vanloo, Gisèle Degeest, Joël Vandekerckhove, Pascale Zimmermann, Nitin Bhardwaj,…

  Source: Cellular and molecular life sciences : CMLS. 2009 Dec

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• A kelch beta propeller featuring as a G beta structural mimic: reinventing the wheel?

  New genetic and protein interaction data suggest that G protein alpha subunits may have partners with primary sequences that are quite divergent. How …

  Authors: Jan Gettemans, Kris Meerschaert, Joel Vandekerckhove, Veerle De Corte

  Source: Science's STKE : signal transduction knowledge environment. 2003 Jul 15

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• Fragmin60 encodes an actin-binding protein with a C2 domain and controls actin Thr-203 phosphorylation in Physarum plasmodia and sclerotia.

  We report the isolation of a cDNA clone encoding a 60-kDa protein termed fragmin60 that cross-reacts with fragmin antibodies. Unlike other gelsolin-re…

  Authors: Tatyana Sklyarova, Veerle De Corte, Kris Meerschaert, Liesbeth Devriendt, Berlinda Vanloo, Juliet Bailey, Lynnette J Cook, Mark Goethals, Jozef Van Damme, Magda Puype,…

  Source: The Journal of biological chemistry. 2002 Oct 18

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