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Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice.
Cancer patients receiving epidermal growth factor receptor (EGFR) antibody therapy often experience an acneiform rash of uncertain etiology in skin re…
Authors: David Surguladze, Dhanvanthri Deevi, Nidia Claros, Erik Corcoran, Su Wang, Mary Jane Plym, Yan Wu, Jacqueline Doody, David J Mauro, Larry Witte,…
Source: Cancer research. 2009 Jul 15
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Outcome of patients with a positive sentinel lymph node who do not undergo completion lymphadenectomy.
BACKGROUND: Completion lymph node dissection (CLND), although considered a standard approach for patients with melanoma and a positive sentinel lymph …
Authors: T Peter Kingham, Katherine S Panageas, Charlotte E Ariyan, Klaus J Busam, Mary Sue Brady, Daniel G Coit
Source: Annals of surgical oncology. 2010 Feb
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Merkel cell carcinoma: histologic features and prognosis.
BACKGROUND: Currently, little is known regarding the potential prognostic value of histologic features in primary cutaneous neuroendocrine (Merkel cel…
Authors: Aleodor A Andea, Daniel G Coit, Bijal Amin, Klaus J Busam
Source: Cancer. 2008 Nov 1
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Merkel cell carcinoma: review.
Merkel cell carcinoma (MCC) is synonymous with primary cutaneous neuroendocrine carcinoma. It tends to affects elderly whites, but there is also an in…
Authors: Melissa P Pulitzer, Bijal D Amin, Klaus J Busam
Source: Advances in anatomic pathology. 2009 May
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Sentinel lymph node biopsy for patients with diagnostically controversial Spitzoid melanocytic tumors?
The distinction of a Spitz nevus from melanoma can be very difficult. Pathologists may disagree on whether a Spitzoid melanocytic proliferation is ben…
Authors: Klaus J Busam, Melissa Pulitzer
Source: Advances in anatomic pathology. 2008 Sep
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Primary cutaneous melanoma with regression does not require a lower threshold for sentinel lymph node biopsy.
INTRODUCTION: Histological evidence of primary tumor regression (RG) is observed in 35% or fewer patients with cutaneous melanoma. Some advocate a low…
Authors: Katherine T Morris, Klaus J Busam, Suzannah Bero, Ami Patel, Mary S Brady
Source: Annals of surgical oncology. 2008 Jan
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Cutaneous desmoplastic melanoma.
Desmoplastic melanoma (DM) is a fibrosing variant of spindle cell melanoma. It most often presents as an indurated lesion in chronically sun-damaged s…
Authors: Klaus J Busam
Source: Advances in anatomic pathology. 2005 Mar
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Differential CD52 expression by distinct myeloid dendritic cell subsets: implications for alemtuzumab activity at the level of antigen presentation in allogeneic graft-host interactions in transplantation.
Alemtuzumab (anti-CD52; Campath 1-H) depletes both host and donor T cells when used in preparative regimens for allogeneic transplantation. This promo…
Authors: Gudrun Ratzinger, John L Reagan, Glenn Heller, Klaus J Busam, James W Young
Source: Blood. 2003 Feb 15
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Yield and predictors of radiologic studies for identifying distant metastases in melanoma patients with a positive sentinel lymph node biopsy.
BACKGROUND: It is common to obtain radiological studies around the time of a positive sentinel lymph node biopsy (SLNB) to exclude patients with dista…
Authors: Jason S Gold, David P Jaques, Klaus J Busam, Mary S Brady, Daniel G Coit
Source: Annals of surgical oncology. 2007 Jul
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Distinction of conjunctival melanocytic nevi from melanomas by fluorescence in situ hybridization.
A conjunctival melanocytic nevus may on occasion be difficult to distinguish from melanoma both clinically and histopathologically. An unambiguous cor…
Authors: Klaus J Busam, Yuqiang Fang, Suresh C Jhanwar, Melissa P Pulitzer, Brian Marr, David H Abramson
Source: Journal of cutaneous pathology. 2010 Feb
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