1 to 10 of 39 literature results

• Frequent p16-independent inactivation of p14ARF in human melanoma.

  BACKGROUND: The tumor suppressors p14(ARF) (ARF) and p16(INK4A) (p16) are encoded by overlapping reading frames at the CDKN2A/INK4A locus on chromosom…

  Authors: Daniel E Freedberg, Sushila H Rigas, Julie Russak, Weiming Gai, Margarita Kaplow, Iman Osman, Faye Turner, Juliette A Randerson-Moor, Alan Houghton, Klaus Busam,…

  Source: Journal of the National Cancer Institute. 2008 Jun 4

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• Positive nonsentinel node status predicts mortality in patients with cutaneous melanoma.

  While sentinel lymph node biopsy (SLN) is a highly accurate and well-tolerated procedure for patients with cutaneous melanoma, the role of the complet…

  Authors: Charlotte Ariyan, Mary Sue Brady, Mithat Gönen, Klaus Busam, Daniel Coit

  Source: Annals of surgical oncology. 2009 Jan

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• Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample.

  BACKGROUND: Germline mutations in the CDKN2A gene have been linked to melanoma incidence in many families with multiple cases of the disease. Previous…

  Authors: Colin B Begg, Irene Orlow, Amanda J Hummer, Bruce K Armstrong, Anne Kricker, Loraine D Marrett, Robert C Millikan, Stephen B Gruber, Hoda Anton-Culver, Roberto Zanetti,…

  Source: Journal of the National Cancer Institute. 2005 Oct 19

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• Experience with 31 sentinel lymph node biopsies for sarcomas and carcinomas in pediatric patients.

  BACKGROUND: Few data exist regarding techniques, indications, and outcomes for sentinel lymph node biopsy in pediatric patients with sarcomas and carc…

  Authors: Mark L Kayton, Ruby Delgado, Klaus Busam, Hiram S Cody, Edward A Athanasian, Daniel Coit, Michael P La Quaglia

  Source: Cancer. 2008 May 1

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• Primary male neuroendocrine adenocarcinoma involving the nipple simulating Merkel cell carcinoma - a diagnostic pitfall.

  Male breast cancer is a rare entity accounting for < 1% of all breast cancer cases in the United States, but with a rate that has been rising over the…

  Authors: Patricia Mecca, Klaus Busam

  Source: Journal of cutaneous pathology. 2008 Feb

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• Determinants of BRAF mutations in primary melanomas.

  The RAS/mitogen-activated protein kinase pathway sends external growth-promoting signals to the nucleus. BRAF, a critical serine/threonine kinase in t…

  Authors: Janet L Maldonado, Jane Fridlyand, Hetal Patel, Ajay N Jain, Klaus Busam, Toshiro Kageshita, Tomomichi Ono, Donna G Albertson, Dan Pinkel, Boris C Bastian

  Source: Journal of the National Cancer Institute. 2003 Dec 17

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• Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma.

  Natural variation in the coding region of the melanocortin-1 receptor (MC1R) gene is associated with constitutive pigmentation phenotypes and developm…

  Authors: Peter A Kanetsky, Timothy R Rebbeck, Amanda J Hummer, Saarene Panossian, Bruce K Armstrong, Anne Kricker, Loraine D Marrett, Robert C Millikan, Stephen B Gruber, Hoda Anton Culver,…

  Source: Cancer research. 2006 Sep 15

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• HDM2 protein overexpression and prognosis in primary malignant melanoma.

  Overexpression of the oncogene HDM2 is observed in a substantial proportion of melanomas, including noninvasive and thin lesions, suggesting that HDM2…

  Authors: David Polsky, Kate Melzer, Carole Hazan, Katherine S Panageas, Klaus Busam, Maria Drobnjak, Hideko Kamino, Joanna G Spira, Alfred W Kopf, Alan Houghton,…

  Source: Journal of the National Cancer Institute. 2002 Dec 4

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• Analysis of BRAF and N-RAS mutations in metastatic melanoma tissues.

  We examined mutations in BRAF exons 11 and 15 and N-RAS exons 2 and 3, in 77 metastatic melanoma cases and 11 melanoma cell lines. Significant differe…

  Authors: Alexis Gorden, Iman Osman, Weiming Gai, Dan He, Weiqing Huang, Anne Davidson, Alan N Houghton, Klaus Busam, David Polsky

  Source: Cancer research. 2003 Jul 15

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• Dermatologists, general practitioners, and the best method to biopsy suspect melanocytic neoplasms.

  Authors: Ashfaq A Marghoob, Vitaly Terushkin, Stephen W Dusza, Klaus Busam, Alon Scope

  Source: Archives of dermatology. 2010 Mar

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