1 to 10 of 17 literature results

• Breaking tolerance to self, circulating natural killer cells expressing inhibitory KIR for non-self HLA exhibit effector function after T cell-depleted allogeneic hematopoietic cell transplantation.

  Alloreactive natural killer (NK) cells are an important influence on hematopoietic stem cell transplantation (HSCT) outcome. In HLA-mismatched HSCT, a…

  Authors: Junli Yu, Jeffrey M Venstrom, Xiao-Rong Liu, James Pring, Reenat S Hasan, Richard J O'Reilly, Katharine C Hsu

  Source: Blood. 2009 Apr 16

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• Inhibitory killer Ig-like receptor genes and human leukocyte antigen class I ligands in haematopoietic stem cell transplantation.

  Identification of inhibitory killer Ig-like receptor (KIR) genes and their cognate human leukocyte antigen (HLA) class I ligands in donor-recipient pa…

  Authors: Bo Dupont, Katharine C Hsu

  Source: Current opinion in immunology. 2004 Oct

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• Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes.

  Inhibitory killer immunoglobulin (Ig)-like receptors (KIRs) recognize HLA-C and -B epitopes on target cells, thereby regulating natural killer (NK) ce…

  Authors: Katharine C Hsu, Carolyn A Keever-Taylor, Andrew Wilton, Clara Pinto, Glenn Heller, Knarik Arkun, Richard J O'Reilly, Mary M Horowitz, Bo Dupont

  Source: Blood. 2005 Jun 15

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• Natural killer cell receptors: regulating innate immune responses to hematologic malignancy.

  Critical to innate immunity, the natural killer (NK) cell performs its function of immunosurveillance through its recognition of altered or missing se…

  Authors: Katharine C Hsu, Bo Dupont

  Source: Seminars in hematology. 2005 Apr

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• The killer cell immunoglobulin-like receptor (KIR) genomic region: gene-order, haplotypes and allelic polymorphism.

  Recent genetic studies have established that the killer cell immunoglobulin-like receptor (KIR) genomic region displays extensive diversity through va…

  Authors: Katharine C Hsu, Shohei Chida, Daniel E Geraghty, Bo Dupont

  Source: Immunological reviews. 2002 Dec

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• Infusion of haplo-identical killer immunoglobulin-like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation.

  Killer immunoglobulin-like receptor (KIR)-ligand mismatched natural killer (NK) cells play a key role in achieving durable remission after haplo-ident…

  Authors: Jumei Shi, Guido Tricot, Susann Szmania, Nancy Rosen, Tarun K Garg, Priyangi A Malaviarachchi, Amberly Moreno, Bo Dupont, Katharine C Hsu, Lee Ann Baxter-Lowe,…

  Source: British journal of haematology. 2008 Dec

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• KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

  PURPOSE: NK cells exhibit cytotoxicity against neuroblastoma. Gene polymorphisms governing NK cell function, therefore, may influence prognosis. Two h…

  Authors: Jeffrey M Venstrom, Junting Zheng, Nabila Noor, Karen E Danis, Alice W Yeh, Irene Y Cheung, Bo Dupont, Richard J O'Reilly, Nai-Kong V Cheung, Katharine C Hsu

  Source: Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Dec 1

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• Hierarchy of the human natural killer cell response is determined by class and quantity of inhibitory receptors for self-HLA-B and HLA-C ligands.

  The interaction of NK inhibitory killer Ig-like receptors (KIRs) with self-MHC class I molecules mediates NK tolerance to self while conferring functi…

  Authors: Junli Yu, Glenn Heller, Joseph Chewning, Sungjin Kim, Wayne M Yokoyama, Katharine C Hsu

  Source: Journal of immunology (Baltimore, Md. : 1950). 2007 Nov 1

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• KIR2DS1-positive NK cells mediate alloresponse against the C2 HLA-KIR ligand group in vitro.

  The inhibitory 2DL1 and activating 2DS1 killer Ig-like receptors (KIR) both have shared ligand specificity for codon sequences in the C2 group HLA-Cw …

  Authors: Joseph H Chewning, Charlotte N Gudme, Katharine C Hsu, Annamalai Selvakumar, Bo Dupont

  Source: Journal of immunology (Baltimore, Md. : 1950). 2007 Jul 15

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• Natural killer cells: tolerance to self and innate immunity to viral infection and malignancy.

  Authors: Wayne M Yokoyama, Marcus Altfeld, Katharine C Hsu

  Source: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2010 Jan

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